Prognostic significance of impairment of heart rate response to exercise impact of left ventricular function and myocardial ischemia
Prognostic significance of impairment of heart rate response to exercise impact of left ventricular function and myocardial ischemia
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DOI：
10.1016/s0735-1097(03)00832-5
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发表时间：
2003-09-03
影响因子：
24
通讯作者：
Pellikka, PA
中科院分区：
文献类型：
--
作者：
Elhendy, A;Mahoney, DW;Pellikka, PA
本研究的目的是研究心率（HR）对运动的反应与死亡和心肌梗死（MI）风险之间的关系，在调整左心室（LV）功能和心肌缺血后。背景运动试验中变时性功能不全与死亡率增加有关。方法我们研究了3,221例患者（年龄59 ± 12岁，男性1,701例），这些患者接受了平板运动超声心动图检查。我们考虑了变时性功能不全的两个标志：1）未能达到最大预测HR的85%，2）低（
OBJECTIVES The goal of this research was to study the association between heart rate (HR) response to exercise and the risk of death and myocardial infarction (MI) after adjustment for left ventricular (LV) function and myocardial ischemia.BACKGROUND Chronotropic incompetence during exercise testing is associated with increased mortality. It is unknown whether LV dysfunction or ischemia accounts for this.METHODS We studied 3,221 patients (age 59 +/- 12 years; 1,701 men) who underwent treadmill exercise echocardiography. We considered two markers of chronotropic incompetence: 1) failure to achieve 85% of the maximal predicted HR, and 2) low (