Transposons and genome evolution in plants
Transposons and genome evolution in plants
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DOI：
10.1073/pnas.97.13.7002
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发表时间：
2000-06-20
影响因子：
11.1
通讯作者：
Fedoroff, N
中科院分区：
文献类型：
--
作者：
Fedoroff, N
虽然今天我们知道转座子在许多生物体的基因组中占很大一部分，但在前半个世纪的遗传分析中，它们一直没有被发现，即使被发现，它们的普遍性和丰度也有一段时间没有被认识到。这种转座子的遗传不可见性将注意力集中在控制转座子和非法重组的机制上。本论文认为，控制转位的机制反映了真核生物通过抑制染色质结构检测、标记和保留复制DNA的更一般的能力。
Although it is known today that transposons comprise a significant fraction of the genomes of many organisms, they eluded discovery through the first half century of genetic analysis and even once discovered, their ubiquity and abundance were not recognized for some time. This genetic invisibility of transposons focuses attention on the mechanisms that control not only transposition, but illegitimate recombination. The thesis is developed that the mechanisms that control transposition are a reflection of the more general capacity of eukaryotic organisms to detect, mark, and retain duplicated DNA through repressive chromatin structures.