Solitary skeletal lesions as primary manifestations of non-Hodgkin's lymphoma
Solitary skeletal lesions as primary manifestations of non-Hodgkin's lymphoma
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孤立性骨骼病变是非霍奇金淋巴瘤的主要表现
DOI：
10.1007/bf00441617
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发表时间：
1994
影响因子：
2.3
通讯作者：
S. Braitinger
中科院分区：
文献类型：
--
作者：
A. Schmidt;D. Kohn;J. Bernhards;S. Braitinger
两名下肢孤立性骨骼病变患者最终被诊断为高度恶性B细胞非霍奇金淋巴瘤。在这两种情况下，分期均未发现其他淋巴结或结外受累。一名患者出现症状已有两年多，最初表现为慢性滑膜炎。第二名患者的左膝近期出现轻微劳累性疼痛。在他的病例中，最初的 X 光平片显示几乎没有骨破坏的证据，而磁共振成像显示左侧胫骨平台存在广泛的病变。骨科医生应了解原发性骨淋巴瘤的鉴别诊断。除了普通 X 射线和闪烁扫描成像之外，早期使用磁共振成像有助于早期活检，从而有助于早期治疗。磁共振成像应被视为淋巴瘤病灶随访检查的首选方法。
Two patients with solitary skeletal lesions of the lower extremity were eventually diagnosed as having high-grade malignant B-cell non-Hodgkin's lymphoma. In both cases staging revealed no other nodal or extranodal involvement. One patient had been symptomatic for more than 2 years, presenting originally as a case of chronic synovitis. The second patient presented with slight exertional pain in his left knee of relatively recent history. In his case the initial plain X-ray showed little evidence of bony destruction, while magnetic resonance imaging revealed an extensive lesion in the left tibial plateau. Orthopedic surgeons should be aware of the differential diagnosis of primary lymphoma of bone. Early use of magnetic resonance imaging, in addition to plain X-ray and scintigraphic imaging, can be helpful in leading to an early biopsy and consequently early treatment. Magnetic resonance imaging should be regarded as the method of choice for follow-up examinations of lymphoma lesions.
影响因子：
11.2
作者：
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana
通讯作者：
P. Carbone;H. Kaplan;K. Musshoff;D. Smithers;M. Tubiana