Rabies

Rabies
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DOI:
10.1016/j.ncl.2008.03.010
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发表时间:
2008-08-01
期刊:
影响因子:
2.4
通讯作者:
Jackson, Alan C.
Jackson, Alan C.
中科院分区:
医学4区
文献类型:
--
作者:
Jackson, Alan C.

文献摘要

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狂犬病在发展中国家仍然是一个重要的公共卫生问题,在发达国家,由于野生动物宿主,狂犬病的本土威胁继续存在。在北美和欧洲,医生通常直到临床病程后期或死亡后才考虑狂犬病的诊断,即使有典型的临床表现。狂犬病病毒的传播与组织移植有关,最近也与器官移植有关。2004年,威斯康星州一名年轻的狂犬病患者幸存下来,但这种有利结果的原因仍然难以捉摸。本文综述了狂犬病神经系统方面的最新信息和进展。
Rabies remains an important public health problem in developing countries, and the indigenous threat of rabies continues in developed countries because of wildlife reservoirs. A diagnosis of rabies is often not considered by physicians until late in the clinical course or after death in North America and Europe, even with typical clinical presentations. Transmission of rabies virus has occurred in association with transplantation of tissues and also recently with organs. In 2004 a young patient survived rabies in Wisconsin, but the reasons for this favorable outcome remain elusive. This article reviews current information and developments on a variety of neurologic aspects of rabies.