The Effects of Mindfulness and Meditation on Vagally Mediated Heart Rate Variability: A Meta-Analysis.

The Effects of Mindfulness and Meditation on Vagally Mediated Heart Rate Variability: A Meta-Analysis.
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DOI:
10.1097/psy.0000000000000900
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发表时间:
2021-07-01
影响因子:
3.3
通讯作者:
Morris ME
Morris ME
中科院分区:
医学3区
文献类型:
--
作者:
Brown L;Rando AA;Eichel K;Van Dam NT;Celano CM;Huffman JC;Morris ME

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Heart Rate Variability (HRV) is a marker of autonomic nervous system function associated with both physical and mental health. Many studies have suggested that mindfulness and meditation-based interventions (MBIs) are associated with improvements in HRV, but findings are mixed and to date no comprehensive meta-analysis has synthesized results. Systematic literature searches were conducted using PsycINFO, Embase, Medline, CINAHL, ERIC and Scopus to identify randomized controlled trials (RCTs) investigating the effects of predominantly seated MBIs on resting-state vagally-mediated HRV. Risk of bias was judged using the Cochrane Risk of Bias tool. Nineteen RCTs met criteria for inclusion in the meta-analysis. Random-effects meta-analysis found that MBIs were not efficacious in increasing vagally-mediated resting-state HRV relative to control conditions (Hedges’ g = 0.38, 95% CI = − 0.014 to 0.77). When removing an outlier (g = 3.22), the effect size was reduced, confidence interval narrowed, and findings remained non-significant (g = 0.19, 95% CI = −0.02 to 0.39). High heterogeneity in results (I2 = 89.12%) could not be explained by a priori determined moderators including intervention duration, study setting and control type. There is currently insufficient evidence to indicate that MBIs lead to improvements in vagally-mediated HRV over control conditions. Future large, well-designed RCTs with low risk of methodological bias could help add to the current evidence to elucidate any role MBIs might play in impacting HRV.