Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
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DOI：
10.1093/cid/ciaa761
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发表时间：
2020-11-15
影响因子：
11.8
通讯作者：
Cohen, Seth A.
中科院分区：
文献类型：
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作者：
Mani, Nandita S.;Budak, Jehan Z.;Cohen, Seth A.
背景。在2019冠状病毒病（COVID - 19）大流行一线工作的医护人员（HCWs）在某些情况下因严重急性呼吸综合征冠状病毒2（SARS - CoV - 2）感染的风险增加。在类似的疫情中已有医院获得性感染的报道，但在美国，医护人员中COVID - 19的患病率及其相关临床结果的数据有限。
方法。我们在华盛顿州西雅图建立了2个高通量员工检测中心，为华盛顿大学医学系统及其附属机构中有症状的员工提供免下车和步行通过两种检测方式。利用这些检测中心的数据，我们报告了有症状员工中SARS - CoV - 2感染的患病率，并描述了COVID - 19患者的临床特征和结果。
结果。2020年3月12日至2020年4月23日期间，在2个员工检测中心对3477名有症状的员工进行了COVID - 19检测；185名（5.3%）员工COVID - 19检测呈阳性。比较一线医护人员（5.2%）和非一线工作人员（5.5%）时，SARS - CoV - 2的患病率相似。在确诊后至少14天接受随访的174名阳性员工中，6人报告因COVID - 19相关疾病住院；所有人均已康复。
结论。在研究期间，我们观察到有症状的医护人员中SARS - CoV - 2检测阳性的患病率与有症状的非一线工作人员相当。在此次大流行期间，员工能够可靠且快速地进行检测对于维护医护人员的健康、安全以及医护人员的可工作状态至关重要，并且有助于SARS - CoV - 2检测阴性的员工快速返回工作岗位。
Background. Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States.Methods. We established 2 high-throughput employee testing centers in Seattle, Washington, with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19.Results. Between 12 March 2020 and 23 April 2020, 3477 symptomatic employees were tested for COVID-19 at 2 employee testing centers; 185 (5.3%) employees tested positive for COVID-19. The prevalence of SARS-CoV-2 was similar when comparing frontline HCWs (5.2%) with nonfrontline staff (5.5%). Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered.Conclusions. During the study period, we observed that the prevalence of positive SARS-CoV-2 tests among symptomatic HCWs was comparable to that of symptomatic nonfrontline staff Reliable and rapid access to testing for employees is essential to preserve the health, safety, and availability of the healthcare workforce during this pandemic and to facilitate the rapid return of SARS-CoV-2-negative employees to work.