Critical particle size for fractionation by deterministic lateral displacement
Critical particle size for fractionation by deterministic lateral displacement
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DOI：
10.1039/b515371a
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发表时间：
2006-01-01
期刊：
影响因子：
6.1
通讯作者：
Sturm, JC
中科院分区：
文献类型：
--
作者：
Inglis, DW;Davis, JA;Sturm, JC
最近，通过确定性横向位移，基于微柱阵列中的小颗粒的尺寸，以前所未有的分辨率证明了液体中的小颗粒的分级（L。R. Huang，E. C.考克斯河H.奥斯汀和JC Sturm，Science，2004，304，987-990，参考文献1）。在本文中，我们提出了一个模型，如何分馏的临界颗粒大小取决于微柱的几何形状，具体取决于差距的职位之间，在一行中的职位相对于另一个偏移，以及流体是否是由流体动力学或电渗驱动。通常，临界颗粒直径远小于差距，这防止了堵塞。该模型得到了2.3 - 22 μ m颗粒数据的支持。
The fractionation of small particles in a liquid based on their size in a micropost array by deterministic lateral displacement was recently demonstrated with unprecedented resolution ( L. R. Huang, E. C. Cox, R. H. Austin and J.C. Sturm, Science, 2004, 304, 987-990, ref. 1). In this paper, we present a model of how the critical particle size for fractionation depends on the micropost geometry, depending specifically on the gap between posts, the offset of posts in one row with respect to another, and whether the fluid is driven by hydrodynamics or by electroosmosis. In general the critical particle diameter is much smaller than the gap, which prevents clogging. The model is supported by data with particles from 2.3 to 22 mu m.