Spineless-aristapedia: a homeotic gene that does not control the development of specific compartments in Drosophila.

Spineless-aristapedia: a homeotic gene that does not control the development of specific compartments in Drosophila.
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无刺无刺足:一种同源异型基因,不控制果蝇特定区室的发育。

DOI:
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发表时间:
1982
期刊:
影响因子:
3.3
通讯作者:
G. Struhl
G. Struhl
中科院分区:
生物学2区
文献类型:
--
作者:
G. Struhl

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A two-step screen for isolating null mutations of the spineless-aristapedia locus has been performed, and several amorphic mutations, as well as a small deficiency, have been obtained. With the exception of the deficiency, which deletes genes required for viability on either side of the spineless-aristapedia locus, these mutations result in a transformation of only the distal antenna into distal leg, thereby indicating that the spineless-aristapedia gene is required for specifying antennal as opposed to leg development in only the distal portion of the antenna. Because this distal region does not appear to be a developmental compartment, it is probable that the spineless-aristapedia gene, unlike several other homeotic genes, is required for maintaining the correct determined state in a population of cells defined by their relative position, not by their ancestry.