Problem-Solving Therapy for Psychological Distress in Japanese Early-stage Breast Cancer Patients

Problem-Solving Therapy for Psychological Distress in Japanese Early-stage Breast Cancer Patients
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DOI:
10.1093/jjco/hys158
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发表时间:
2012-12-01
影响因子:
2.4
通讯作者:
Akechi, Tatsuo
Akechi, Tatsuo
中科院分区:
医学4区
文献类型:
--
作者:
Hirai, Kei;Motooka, Hiroko;Akechi, Tatsuo

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本报告提供了一项II期临床试验的结果,该试验是关于日本早期乳腺癌患者所经历的心理困扰的问题解决疗法的有效性和可行性。参与者是36名在日本大坂府一所大学医院接受手术后的日本乳腺癌患者。在使用痛苦和影响温度计和医院焦虑和抑郁量表筛选心理困扰后,高度困扰的患者每周接受5次问题解决治疗计划,19名患者完成了干预和随访。干预前和3个月随访时医院焦虑和抑郁量表总分存在显著差异(P 0.02),干预前到随访时的平均变化评分为6.05(SD 1.94)。干预有一个大的效应量(d 0.82)。此外,在担心,自我效能和生活质量的措施显着的变化,我们的研究结果表明,解决问题的治疗计划有可能是有效的,以减轻日本早期乳腺癌患者所经历的心理困扰。该计划的真正有效性应通过未来的随机对照试验来证实。
The current report provides the result of a Phase II clinical trial regarding the effectiveness and feasibility of problem-solving therapy for psychological distress experienced by Japanese early-stage breast cancer patients.Participants were 36 post-surgery Japanese breast cancer patients in a university hospital located in Osaka Prefecture, Japan. After screening for psychological distress using the Distress and Impact Thermometer and the Hospital Anxiety and Depression Scale, highly distressed patients were exposed to 5 weekly sessions of the problem-solving therapy program.Nineteen patients completed the intervention and follow-up. There was a significant difference between the pre-intervention and the 3-month follow-up in the total Hospital Anxiety and Depression Scale score (P 0.02), and the mean change score from the pre-intervention to the follow-up was 6.05 (SD 1.94). The intervention had a large effect size (d 0.82). There were also significant changes in worry, self-efficacy and quality of life measures.The findings of our study suggest that the problem-solving therapy program has potential to be effective for alleviating psychological distress experienced by Japanese early-stage breast cancer patients. The true effectiveness of the program should be confirmed by a future randomized control trial.