Transcatheter mitral valve implantation for degenerated mitral bioprostheses or failed surgical annuloplasty rings: A systematic review and meta-analysis.

Transcatheter mitral valve implantation for degenerated mitral bioprostheses or failed surgical annuloplasty rings: A systematic review and meta-analysis.
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经导管二尖瓣植入治疗退化的二尖瓣生物假体或失败的手术瓣环成形术环:系统评价和荟萃分析。

DOI:
10.1111/jocs.13767
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发表时间:
2018-09
影响因子:
1.6
通讯作者:
Zhou Y
Zhou Y
中科院分区:
医学4区
文献类型:
--
作者:
Hu J;Chen Y;Cheng S;Zhang S;Wu K;Wang W;Zhou Y

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经导管二尖瓣置入术(TMVIV)和二尖瓣环置入术(TMVIR)治疗退行性二尖瓣生物瓣和失败的二尖瓣成形环最近已成为不适合再次手术的患者的治疗选择。系统的文献综述被用来总结接受TMVIV和TMVIR手术的患者的基线特征和临床结果。共有245名患者(172名接受TMVIV手术的患者和73名接受TMVIR手术的患者)纳入研究;93.5%的患者成功地植入了TMVIV或TMVIR。出院时、30天和6个月的死亡率分别为5.7%、8.1%和23.4%。大多数手术(55.2%)采用经根尖(TA)入路。TA和跨间隔(TS)入路的结果相似。在发生二尖瓣狭窄和以二尖瓣返流为失败模式的患者之间,短期结果没有显著差异。TMVIV和TMVIR植入治疗退行性二尖瓣生物瓣和失败的二尖瓣成形环是安全有效的。对于二尖瓣狭窄或返流的患者,这两种手术都可以通过TA或TS获得良好的短期临床结果,但目前缺乏长期随访数据来确定这些手术的持久性。
Transcatheter mitral valve‐in‐valve (TMVIV) and valve‐in‐ring (TMVIR) implantation for degenerated mitral bioprostheses and failed annuloplasty rings have recently emerged as treatment options for patients deemed unsuitable for repeat surgery. A systematic literature review was conducted to summarize the data regarding the baseline characteristics and clinical outcomes of patients undergoing TMVIV and TMVIR procedures. A total of 245 patients (172 patients who underwent TMVIV surgery and 73 patients who underwent TMVIR surgery) were included in the study; 93.5% of patients experienced successful TMVIV or TMVIR implantation. The mortality rates at discharge, 30 days, and 6 months were 5.7%, 8.1%, and 23.4%, respectively. The transapical (TA) access route was used in most procedures (55.2%). The TA and transseptal (TS) access routes resulted in similar outcomes. No significant differences were observed in the short‐term outcomes between the patients who developed mitral stenosis versus mitral regurgitation as the mode of failure. TMVIV and TMVIR implantation for degenerated mitral bioprostheses and failed annuloplasty rings are safe and effective. Both procedures, via TA or TS access, can result in excellent short‐term clinical outcomes in patients with mitral stenosis or regurgitation, but long‐term follow‐up data are currently lacking to determine the durability of these procedures.
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