Syncope as the Initial Manifestation of Advanced Nasopharyngeal Carcinoma: A Case Report.
Syncope as the Initial Manifestation of Advanced Nasopharyngeal Carcinoma: A Case Report.
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晕厥作为晚期鼻咽癌的首发表现：一例报告
DOI：
10.3389/fcvm.2021.796653
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发表时间：
2021
影响因子：
3.6
通讯作者：
Guo YS
中科院分区：
文献类型：
--
作者：
Zhang SC;Lin MQ;Zhang LW;Lin XQ;Luo MQ;Lin KY;Guo YS
颈动脉窦综合征是老年人晕厥的主要原因。与晚期鼻咽癌转移继发的颈动脉窦综合征相关的晕厥很少发生。目前的研究报道了一名66岁的女性，她以频繁且反复的晕厥病史为首发症状，最终被诊断为晚期鼻咽癌。正电子发射断层扫描诊断为晚期鼻咽癌，累及颈动脉鞘间隙，鼻咽活检显示为非角化鼻咽癌。经诊断和治疗，患者未再出现晕厥。总之，我们的案例研究表明，应高度重视晕厥的潜在内在原因，尤其是鼻咽癌，因为它是一种隐匿的恶性肿瘤，需要精确识别。
Carotid sinus syndrome is a principal cause of syncope in the elderly. Syncope, associated with carotid sinus syndrome which is secondary to metastasis of advanced nasopharyngeal carcinoma, rarely occurs. The current study reported a 66-year-old woman, who presented with a history of frequent and recurrent syncope as the initial symptom, and was eventually diagnosed with advanced nasopharyngeal carcinoma. The positron emission tomography scan demonstrated a diagnosis of advanced nasopharyngeal carcinoma with involvement in carotid sheath space, and nasopharyngeal biopsy revealed non-keratinized nasopharyngeal carcinoma. After diagnosis and treatment, the patient had no recurrence of syncope. In summary, our case study suggests that great importance should be attached to potential intrinsic causes of syncope especially in the case of nasopharyngeal carcinoma, as it is an insidious malignancy which needs to be precisely identified.