Perception of nasal pungency in smokers and nonsmokers

Perception of nasal pungency in smokers and nonsmokers
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吸烟者和非吸烟者对鼻腔刺激性的感知

DOI:
10.1016/0031-9384(82)90246-3
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发表时间:
1982
影响因子:
2.9
通讯作者:
W. Cain
W. Cain
中科院分区:
医学3区
文献类型:
--
作者:
J. Cometto;W. Cain

文献摘要

被引文献

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两个实验探索了吸烟者和非吸烟者之间常见化学敏感性的差异。第一个实验证实并扩展了我们先前的发现,即吸烟者对鼻刺激物(二氧化碳)的反应具有比非吸烟者更高的短潜伏期反射性暂时性呼吸暂停阈值。实验表明,即使在测量前短时间吸烟(6-10分钟)也会进一步损害吸烟者对刺激物的敏感性。应用新的缩放技术的幅度匹配,即人们判断的刺激性,气味,并在同一会话中的音调的各种水平的感知幅度,这意味着吸烟者实际上感知刺激不如不吸烟者敏锐。两组受试者对刺激性的心理生理功能表明,不敏感可能是由传导因素引起的(例如,粘液屏障增厚),而不是神经因素。的缩放和那些暂时性呼吸暂停的阈值的结果显示出良好的定量协议,并表示反射的阈值发生在感知辛辣的标准水平。
Two experiments explored the difference in common chemical sensitivity between smokers and nonsmokers. The first experiment confirmed and extended our previous finding that smokers have a higher threshold than nonsmokers for a short-latency, reflex transitory apnea in response to a nasal irritant (carbon dioxide). The experiment revealed that even short periods of smoking (6–10 min) just before the measurement will further impair the smoker's sensitivity to an irritant. Application of the novel scaling technique magnitude matching, whereby persons judged the perceived magnitude of various levels of an irritant, odorant, and tone in the same session, implied that smokers actually perceive irritation less keenly than nonsmokers. The psychophysical functions for pungency in the two groups suggested that the insensitivity may arise from conductive factors (e.g., thickening of the mucus barrier) rather than from neural factors. The results of the scaling and those for the threshold for transitory apnea showed excellent quantitative agreement and indicated that the threshold for the reflex occurred at a criterion level of perceived pungency.