Application of an mRNA-based molecular viability assay to oropharyngeal washes for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. A pilot study.
Application of an mRNA-based molecular viability assay to oropharyngeal washes for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. A pilot study.
复制标题
基于 mRNA 的分子活力测定在口咽冲洗液中的应用，用于诊断 HIV 感染患者的肺孢子菌肺炎。
DOI：
10.1111/j.1550-7408.2003.tb00652.x
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Unnasch,ThomasR
中科院分区：
文献类型：
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作者：
Huang,Laurence;Crothers,Kristina;DeOliveira,Ana;Eiser,Shary;Zucchi,Patrizia;Beard,CharlesB;Unnasch,ThomasR
材料和方法符合条件的受试者是2002年8月至2003年4月（8个月）因临床疑似PcP而入住旧金山弗朗西斯科总医院的HIV感染患者。研究受试者是同意参与研究的患者。受试者前瞻性入组。加州圣弗朗西斯科大学、伯明翰的亚拉巴马大学和疾病控制和预防中心机构审查委员会批准了这项研究。
MATERIALS AND METHODSEligible subjects were HIV-infected patients who were admitted to San Francisco General Hospital with clinically suspected PcP from August 2002 through April 2003 (8 months). Study subjects were patients who consented to study participation. Subjects were prospectively enrolled. The University of California San Francisco, the University of Alabama at Birmingham, and the Centers for Disease Control and Prevention Institutional Review Boards approved the study.