"Adolescent-onset Still's disease": characteristics and outcome in comparison with adult-onset Still's disease.
"Adolescent-onset Still's disease": characteristics and outcome in comparison with adult-onset Still's disease.
复制标题
“青少年斯蒂尔病”：与成人斯蒂尔病相比的特征和结果。
DOI：
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发表时间：
2002
影响因子：
3.7
通讯作者：
A. So
中科院分区：
文献类型：
--
作者：
F. Luthi;P. Zufferey;M. Hofer;A. So
目标
确定青少年发病的全身性幼年特发性关节炎（JIA）和成人发病的斯蒂尔病（AOSD）是否代表相同的疾病临床连续统。
方法
回顾性审查了过去10年内在一所大学医院诊断为斯蒂尔病的所有儿童和成人患者的现有临床数据。通过临床评价和HAQ或c-HAQ评估末次访视时的功能结局。
结果
9例患者被确定为青少年发作的系统性JIA，并与10例AOSD（发病> 18岁）进行了比较。两组在发病时的临床表现和随访时的结局方面无统计学显著差异。
结论
出现全身性JIA的青少年患者的疾病发作和病程与AOSD患者无法区分，这表明他们代表了单一疾病实体的连续体。
OBJECTIVES
To determine if adolescent onset systemic juvenile idiopathic arthritis (JIA) and adult onset Still's disease (AOSD) represent the same clinical continuum of disease.
METHODS
Retrospective review of available clinical data on all pediatric and adult patients diagnosed with Still's disease within the last 10 years at a university hospital. Assessment of functional outcomes at last visit by clinical evaluation and HAQ or c-HAQ.
RESULTS
Nine patients were identified as adolescent onset systemic JIA and were compared with 10 patients with AOSD (onset > 18 years old). No statistically significant differences were found between the two groups in terms of clinical presentation at onset and outcome at follow up.
CONCLUSION
Adolescent patients presenting with systemic JIA have a disease onset and course undistinguishable from that of AOSD patients, suggesting that they represent a continuum of a single disease entity.