Transurethral laser coagulation for treatment of urinary bladder tumors

Transurethral laser coagulation for treatment of urinary bladder tumors
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经尿道激光凝固治疗膀胱肿瘤

DOI:
10.1002/lsm.1900020308
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发表时间:
1983
影响因子:
2.4
通讯作者:
PhD F. Frank
PhD F. Frank
中科院分区:
医学3区
文献类型:
--
作者:
MD K. Rothenberger;J. Pensel;MD DlPL PHYS;MD A. Hofstetter;MD E. Keiditsch;PhD F. Frank

文献摘要

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由于所涉及的生物物理特性,Nd:YAG激光最适合凝固甚至不均匀的组织。我们确定了最佳的激光治疗膀胱肿瘤的参数。可以获得深均匀的坏死,而没有膀胱壁穿孔的风险,并且该手术不会对肠袢造成危险的损伤。我们通过仔细检查和系统调查研究了动物实验,因此我们能够根据组织厚度确定足够的激光参数。临床研究证实了这些结果的活的人体组织。经过几年的临床使用的Nd:YAG激光器,我们可以作出第一个统计报表。
Owing to the biophysical properties involved, the Nd:YAG laser is most suited for coagulation of even inhomogeneous tissue. We determined the optimal laser parameters for therapy of urinary bladder tumors. Deep homogeneous necroses can be obtained without perforation risk of the bladder wall, and the procedure does not cause dangerous damage to the intestinal loops. We have studied animal experiments by close examination and systematic inquiry, and thus we were able to determine sufficient laser parameters in dependence on tissue thickness. Clinical studies verified these results for living human tissue. After some years of clinical use of the Nd: YAG laser we can make the first statistical statements.