THYMINE HYDRATE FORMED BY ULTRAVIOLET AND GAMMA IRRADIATION OF AQUEOUS SOLUTIONS

THYMINE HYDRATE FORMED BY ULTRAVIOLET AND GAMMA IRRADIATION OF AQUEOUS SOLUTIONS
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水溶液经紫外线和伽马射线照射形成胸腺嘧啶水合物

DOI：
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发表时间：
1973
期刊：
影响因子：
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通讯作者：
H. E. Johns
H. E. Johns
中科院分区：
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文献类型：
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作者：
G. Fisher;H. E. Johns

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翻译后摘要-证据是提出的形成的胸腺嘧啶水合物后，紫外线（UV）或伽马射线照射的水溶液。UV量子效率表现出对pH的依赖性，类似于尿嘧啶水合所示，但产率比尿嘧啶小三个数量级。水合作用不受波长、氧气或胸腺嘧啶浓度的影响。光水合物转化为胸腺嘧啶的转化率与γ辐解形成的胸腺嘧啶水合物的两种异构体的转化率相似，并且与尿嘧啶光水合物的转化率一样取决于pH值。胸腺嘧啶的光水合物在色谱上与6-羟基-5，6-二氢胸腺嘧啶的顺式异构体相同。
Abstract— Evidence is presented for the formation of a thymine hydrate upon ultraviolet (UV) or gamma irradiation of aqueous solutions. The UV quantum efficiency exhibits a dependence on pH similar to that shown for uracil hydration, but the yield is three orders of magnitude smaller than for uracil. Hydration is not affected by wavelength, oxygen, or concentration of thymine. The reversal rate of the photohydrate to thymine is similar to the reversal rates of both isomers of the thymine hydrate formed by γ radiolysis, and depends on pH in the same way as the rate for the uracil photohydrate. The photohydrate of thymine is chromatographically identical to the cis isomer of 6‐hydroxy‐5, 6‐dihydrothymine.