MR fingerprinting for rapid quantification of myocardial T(1) , T(2) , and proton spin density.
MR fingerprinting for rapid quantification of myocardial T(1) , T(2) , and proton spin density.
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DOI：
10.1002/mrm.26216
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发表时间：
2017-04
影响因子：
3.3
通讯作者：
Seiberlich, Nicole
中科院分区：
文献类型：
--
作者：
Hamilton, Jesse I.;Jiang, Yun;Chen, Yong;Ma, Dan;Lo, Wei-Ching;Griswold, Mark;Seiberlich, Nicole
目的：介绍二维磁共振指纹技术定量心肌T1、T2和M0。介绍了一种ecg触发的MR指纹（MRF）方法，用于在单次屏气（短至4次心跳）期间绘制心肌T1、T2和M0。脉冲序列采用可变翻转角度、重复次数、反转恢复次数和T2准备减相次数。每次扫描都会模拟可能的信号演变字典，其中包含受试者心率的独特变化。在模拟中探讨了序列设计的各个方面，并在模拟研究中评估了心脏磁共振成像的准确性和精度。11名志愿者在3T时进行体内成像以生成原生参数图。所提出的心脏MRF序列的T1和T2测量值与幻影研究中的标准自旋回波测量值相关良好（R2>0.99）。Bland-Altman分析显示，MRF和MOLLI之间的心肌T1测量值（偏差为1ms， 95%一致性范围为- 72至72ms）和MRF和T2制备的bSSFP之间的T2测量值（偏差为- 2.6ms， 95%一致性范围为- 8.5至3.3ms）具有良好的一致性。磁共振成像（MRF）可以在单次屏住呼吸的情况下提供定量的单片心脏T1、T2和M0图。
To introduce a 2D MR Fingerprinting technique for quantification of T1, T2, and M0 in myocardium. An ECG-triggered MR Fingerprinting (MRF) method is introduced for mapping myocardial T1, T2, and M0 during a single breathhold in as short as four heartbeats. The pulse sequence employs variable flip angles, repetition times, inversion recovery times, and T2 preparation dephasing times. A dictionary of possible signal evolutions is simulated for each scan that incorporates the subject’s unique variations in heart rate. Aspects of the sequence design were explored in simulations, and the accuracy and precision of cardiac MRF were assessed in a phantom study. In vivo imaging was performed at 3T in eleven volunteers to generate native parametric maps. T1 and T2 measurements from the proposed cardiac MRF sequence correlated well with standard spin echo measurements in the phantom study (R2>0.99). A Bland-Altman analysis revealed good agreement for myocardial T1 measurements between MRF and MOLLI (bias 1ms, 95% limits of agreement −72 to 72ms) and T2 measurements between MRF and T2-prepared bSSFP (bias −2.6ms, 95% limits of agreement −8.5 to 3.3ms). MRF can provide quantitative single slice T1, T2, and M0 maps in the heart within a single breathhold.
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DOI：
10.1186/1532-429x-14-15
发表时间：
2012-02-06
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Dall'Armellina E;Piechnik SK;Ferreira VM;Si QL;Robson MD;Francis JM;Cuculi F;Kharbanda RK;Banning AP;Choudhury RP;Karamitsos TD;Neubauer S
通讯作者：
Neubauer S
DOI：
10.1186/1532-429x-14-64
发表时间：
2012-09-11
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Kellman P;Wilson JR;Xue H;Bandettini WP;Shanbhag SM;Druey KM;Ugander M;Arai AE
通讯作者：
Arai AE
影响因子：
3.3
作者：
Huang, Teng-Yi;Liu, Yi-Jui;Poncelet, Brigitte P.
通讯作者：
Poncelet, Brigitte P.
影响因子：
3.3
作者：
BRITTAIN, JH;HU, BS;NISHIMURA, DG
通讯作者：
NISHIMURA, DG
DOI：
10.1186/s12968-014-0102-0
发表时间：
2014-12-20
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Kvernby S;Warntjes MJ;Haraldsson H;Carlhäll CJ;Engvall J;Ebbers T
通讯作者：
Ebbers T