The Treatment of Cancer with Fast Neutrons1
The Treatment of Cancer with Fast Neutrons1
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用快中子治疗癌症1
DOI：
10.1148/39.5.608
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发表时间：
1942
期刊：
影响因子：
19.7
通讯作者：
J. C. Larkin
中科院分区：
文献类型：
--
作者：
R. Stone;J. C. Larkin
简介 第一个中子由吉森大学的 Bothe 和 Becker (3) 于 1932 年产生，几个月后被剑桥大学的查德威克 (Chadwick) (4) 鉴定为核粒子。他称它们为中子，因为它们不带电荷。这些加速的粒子被认为是一种新型辐射。 E. O. 劳伦斯发现回旋加速器为生物学研究提供了足够强度的快中子束。到 1938 年，光束准直、回旋加速器屏蔽和生物学研究已经取得了足够的进展，足以证明通过快中子照射来影响人类癌症的尝试是合理的。劳伦斯 (Lawrence) (7) 等人已充分描述了回旋加速器。可以这么说，当它目前用于治疗时，它会电离氘（重氢），从而形成氘核，并将其加速到非常高的能量。当氘核撞击铍目标时，铍中的质子和中子会发生内部转换...
Introduction The first neutrons were produced by Bothe and Becker (3) at the University of Giessen in 1932 and were identified as nuclear particles a few months later by Chadwick (4) at Cambridge. He called them neutrons because they had no electrical charge. These particles, accelerated, were recognized as a new type of radiation. The discovery of the cyclotron by E. O. Lawrence made available beams of fast neutrons of sufficient intensity for biological investigation. By 1938 the collimation of the beam, the shielding of the cyclotron, and biological studies had progressed far enough to justify attempts to Influence cancer in man by irradiation with fast neutrons. The cyclotron has been adequately described by Lawrence (7) and others. Suffice it to say that, as it is used for therapy at present, it ionizes deuterium (heavy hydrogen), and thus forms deuterons which it accelerates to very high energies. When the deuterons strike a beryllium target, an internal conversion of protons and neutrons in the ber...