Vancomycin-resistant enterococcus infection in the hematopoietic stem cell transplant recipient: an overview of epidemiology, management, and prevention.

Vancomycin-resistant enterococcus infection in the hematopoietic stem cell transplant recipient: an overview of epidemiology, management, and prevention.
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DOI:
10.12688/f1000research.11831.1
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
Deresinski S
Deresinski S
中科院分区:
其他
文献类型:
--
作者:
Benamu E;Deresinski S

文献摘要

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耐万古霉素肠球菌(VRE)现在是美国医院感染的主要原因之一。造血干细胞移植(HSCT)受者VRE定植和感染的风险增加。VRE已成为该人群菌血症的主要原因,提出了关于VRE定植和感染在HSCT结局中的作用和影响以及最佳预防和治疗方法的重要临床问题。我们在这里回顾了已发表的文献和科学进展,解决这些棘手的问题,并提供了一个合理的框架,他们的方法。
Vancomycin-resistant enterococcus (VRE) is now one of the leading causes of nosocomial infections in the United States. Hematopoietic stem cell transplantation (HSCT) recipients are at increased risk of VRE colonization and infection. VRE has emerged as a major cause of bacteremia in this population, raising important clinical questions regarding the role and impact of VRE colonization and infection in HSCT outcomes as well as the optimal means of prevention and treatment. We review here the published literature and scientific advances addressing these thorny issues and provide a rational framework for their approach.