Multiple Somatic Symptoms Predict Impaired Health Status in Functional Somatic Syndromes
Multiple Somatic Symptoms Predict Impaired Health Status in Functional Somatic Syndromes
复制标题
DOI：
10.1007/s12529-012-9257-y
复制
发表时间：
2013-06-01
影响因子：
2.7
通讯作者：
McBeth, J.
中科院分区：
文献类型：
--
作者：
Creed, F. H.;Tomenson, B.;McBeth, J.
功能性躯体综合征与多种躯体症状之间的关系尚不清楚，我们评估了躯体症状的数量是否是三种功能性躯体综合征（FSS）健康状况的预测因子，在一项990名英国成年人的基于人群的研究中，我们通过问卷调查和病历资料评估了慢性广泛性疼痛（CWP）、慢性疲劳（CF）和肠易激综合征（IBS）。在基线和1年后的随访中，我们评估了健康状况（简表12和EQ-5D）、躯体症状数量（躯体症状量表）和焦虑/抑郁（医院焦虑和抑郁量表）。在三种功能综合征中，患有FSS的人同时具有多种躯体症状的比例（52- 55%）相似。在基线和随访时，多种躯体症状的存在与更多的健康状况受损相关。这一发现不能用FSS的严重程度来解释。在没有多种躯体症状的情况下，FSS的健康状况为一般或良好。在多元回归分析中，躯体症状的数量、功能综合征（CWP或CF）的存在和焦虑/抑郁是调整混杂因素后随访时EQ-5D温度计的预测因素。FSS患者的多种躯体症状与健康状况受损相关，这不能用更严重的功能综合征或焦虑和抑郁的存在来解释。
The relationship between functional somatic syndromes and multiple somatic symptoms is unclear.We assessed whether the number of somatic symptoms is a predictor of health status in three functional somatic syndromes (FSS).In a population-based study of 990 UK adults we assessed chronic widespread pain (CWP), chronic fatigue (CF) and irritable bowel syndrome (IBS) by questionnaire and medical record data. We assessed health status (Short Form 12 and EQ-5D), number of somatic symptoms (Somatic Symptom Inventory) and anxiety/depression (Hospital Anxiety and Depression Scale) both at baseline and at follow-up 1 year later.The proportion of people with an FSS who also have multiple somatic symptoms (52-55 %) was similar in the three functional syndromes. The presence of multiple somatic symptoms was associated with more impaired health status both at baseline and at follow-up. This finding was not explained by severity of FSS. In the absence of multiple somatic symptoms, the health status of the FSS was fair or good. In multiple regression analysis, the number of somatic symptoms, the presence of a functional syndrome (CWP or CF) and anxiety/depression were predictors of EQ-5D thermometer at follow-up after adjustment for confounders.Multiple somatic symptoms in people with an FSS are associated with impaired health status and this cannot be explained by more severe functional syndrome or the presence of anxiety and depression.