Computed Tomography-Guided Percutaneous Needle Biopsy of Pulmonary Nodules: Impact of Nodule Size on Diagnostic Accuracy
Computed Tomography-Guided Percutaneous Needle Biopsy of Pulmonary Nodules: Impact of Nodule Size on Diagnostic Accuracy
复制标题
DOI：
10.3816/clc.2009.n.049
复制
发表时间：
2009-09-01
影响因子：
3.6
通讯作者：
Hofmann, Lawrence V.
中科院分区：
文献类型：
--
作者：
Kothary, Nishita;Lock, Laura;Hofmann, Lawrence V.
目的：比较计算机断层扫描（CT）引导下经皮肺活检对直径1.5 cm肺结节的诊断准确性和并发症发生率。患者和方法：共有139例患者（年龄范围18-89岁，平均62.5岁）接受了ct引导下经皮细针穿刺活检或使用自动活检枪进行20针穿刺活检。37例患者肺结节直径1.5 cm（平均2.8 cm）。诊断的准确性由细胞病理学结果决定。记录了主要和次要并发症。结果：总体诊断正确率67.6%，气胸率34.5%，开胸管插入率5%。98例恶性肿瘤患者中，77例（78.6%）有明确的活检诊断。总的来说，在统计学上，直径为1.5 cm的结节比直径为1.5 cm的结节更容易被诊断为标本（73.5%）
Purpose: This study was undertaken to compare the diagnostic accuracy and complication rate of computed tomography (CT)-guided percutaneous lung biopsies of lung nodules 1.5 cm in diameter. Patients and Methods: A total of 139 patients (age range, 18-89 years; mean, 62.5 years) underwent CT-guided percutaneous fine-needle aspiration biopsy or 20-gauge core biopsy using an automated biopsy gun. In 37 patients, the lung nodule measured 1.5 cm (mean, 2.8 cm). Diagnostic accuracy was determined by cytopathology results. Major and minor complications were documented. Results: Overall diagnostic accuracy, pneumothorax rate, and thoracostomy tube insertion rates were 67.6%, 34.5%, and 5%, respectively. Of the 98 patients with malignancy, 77 patients (78.6%) had a definite diagnostic biopsy. Overall, nodules > 1.5 cm were statistically more likely to result in a diagnostic specimen (73.5%) than nodules 1.5 cm than in those