E-Cigarette Airflow Rate Modulates Toxicant Profiles and Can Lead to Concerning Levels of Solvent Consumption
E-Cigarette Airflow Rate Modulates Toxicant Profiles and Can Lead to Concerning Levels of Solvent Consumption
复制标题
DOI：
10.1021/acsomega.7b01521
复制
发表时间：
2018-01-01
期刊：
影响因子：
4.1
通讯作者：
Strongin, Robert M.
中科院分区：
文献类型：
--
作者：
Korzun, Tetiana;Lazurko, Maryana;Strongin, Robert M.
近年来，能够增强气流的电子烟越来越受欢迎。这项研究的目的是证明流速调节电子烟中产生的特定气雾剂毒物的水平。到目前为止，涉及电子烟的各种实验室调查中使用的流速差异很大，因此可以促进气雾剂产品轮廓的实验室间变异性。在较低的温度下，羟丙酮和乙醇醛的热分解不那么有利，支持在较高的流速/较低的加热盘管温度下观察到这些产物。较高的温度促进羟丙酮生成乙醛，羟丙酮和乙醇醛生成甲醛。另一项发现是，更大的气流也会使用户接触到令人担忧的电子液体溶剂水平。在所研究的适度条件下，丙二醇气溶胶水平高于NASA定义的可接受吸入水平，并在公认的每日摄入量安全水平范围内。
Electronic cigarettes enabling enhanced airflow have grown in popularity in recent years. The objective of this study is to show that flow rates modulate the levels of specific aerosol toxicants produced in electronic cigarettes. Flow rates used in various laboratory investigations involving e-cigarettes have varied widely to date, and can thus promote interlaboratory variability in aerosol product profiles. The thermal decomposition of hydroxyacetone and glycolaldehyde is less favorable at lower temperatures, supporting the observations of these products at higher flow rates/lower heating coil temperatures. Higher temperatures promote the formation of acetaldehyde from hydroxyacetone and formaldehyde from both hydroxyacetone and glycolaldehyde. A separate finding is that greater airflow can also expose users to concerning levels of e-liquid solvents. Under the modest conditions studied, propylene glycol aerosol levels are found at above the acceptable inhalation levels defined by NASA, and in range of the generally recognized as safe levels for daily ingestion.