Periampullary adenocarcinoma - Analysis of 5-year survivors
Periampullary adenocarcinoma - Analysis of 5-year survivors
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DOI：
10.1097/00000658-199806000-00005
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发表时间：
1998-06-01
影响因子：
9
通讯作者：
Pitt, HA
中科院分区：
文献类型：
--
作者：
Yeo, CJ;Sohn, TA;Pitt, HA
目的回顾一组5年前或5年以上接受胰腺十二指肠切除术治疗壶腹周围腺癌的患者的预后。摘要背景资料表明，对于壶腹周围腺癌，尤其是胰腺肿瘤，切除的益处存在可控性。许多系列只报道了Kaplan-Meier精算的5年存活率。方法自1970年4月至1992年5月，在约翰霍普金斯医院对242例壶腹周围腺癌患者施行了胰腺十二指肠切除术。到1997年5月，完成了后续行动。对所有病理标本进行复习和分类。计算实际5年生存率。比较存活大于或等于5年的患者与切除后存活5年的患者的人口学、术中、病理和术后特征。
ObjectiveThis single-institution experience retrospectively reviews the outcomes in a group of patients treated 5 or more years ago by pancreaticoduodenectomy for periampullary adenocarcinoma.Summary Background DataControversy exists regarding the benefit of resection for periampullary adenocarcinoma, particularly for pancreatic: tumors. Many series report only Kaplan-Meier actuarial 5-year survival rates. There are believed to be discrepancies between the actuarial 5-year survival data and the actual 5-year survival rates.MethodsFrom April 1970 through May 1992, 242 patients underwent pancreaticoduodenal resection for periampullary adenocarcinoma at The Johns Hopkins Hospital. Follow-up was complete through May 1997. All pathology specimens were reviewed and categorized. Actual 5-year survival rates were calculated. The demographic, intraoperative, pathologic, and postoperative features of patients surviving greater than or equal to 5 years were compared with those of patients who survived 5 years after resection.