Fast, visual specialization for reading in English revealed by the topography of the N170 ERP response.
Fast, visual specialization for reading in English revealed by the topography of the N170 ERP response.
复制标题
N170 ERP响应的地形揭示了快速，视觉专业，用于英语阅读。
DOI：
10.1186/1744-9081-1-13
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发表时间：
2005-08-09
影响因子：
5.1
通讯作者：
McCandliss, Bruce D
中科院分区：
文献类型：
--
作者：
Maurer, Urs;Brandeis, Daniel;McCandliss, Bruce D
与视觉词相关的N170效应可能与已被证明用于面部和其他广泛研究的视觉刺激类别的感知专业知识效应有关。虽然面部和其他物体的专业知识的影响通常是双边或右侧，阅读相关的N170效应的空间地形往往是左侧，提供潜在的见解阅读相关的感知专业知识的独特方面。扩展以前的研究在德国，我们使用一个高密度的通道阵列的N170地形特征阅读相关的感知专业知识在英语，一种语言与不一致的拼写到声音映射。与整体阅读相关的专业知识相关的N170效应是通过对比视觉单词与新颖符号串的反应来定义的。通过将这些条件与伪词进行对比，我们研究了这种与阅读相关的N170效应如何推广到有序的新字母串。一个样本的样本排列测试计算的字与符号ERP地形显示在两个时间窗口对应的N170和P300组件的差异。地形质心分析的字和符号N170表现出显着的差异，在两个左右，以及走廊上方的尺寸。文字引起更大的N170负比符号在下枕颞通道，最大的影响，在左下区往往未采样在传统的电极蒙太奇。进一步的对比产生的pseudoword符号的比较和左偏地形的影响，字pseudoword比较优越的地形效果。与阅读体验相关的快速专业化感知产生可在不同EEG系统和不同语言中检测到的N170调制。这种效应的表征可以通过用对较差区域进行采样的更大空间频率记录进行采样来改进。与德语不同，英语阅读相关的专业知识效应在N170对新伪词的反应中只产生了部分概括。地形上的N170优势的差异可能反映了一般的知觉专业知识的正字法字符串，因为它被发现在两种语言的单词和伪词。地形左，右N170词和伪词之间的差异只发现在英语中，并可能表明，由于拼写到声音映射的不一致，在发音新的伪词的歧义影响字母串处理的早期阶段。
N170 effects associated with visual words may be related to perceptual expertise effects that have been demonstrated for faces and other extensively studied classes of visual stimuli. Although face and other object expertise effects are typically bilateral or right-lateralized, the spatial topography of reading-related N170 effects are often left-lateralized, providing potential insights into the unique aspects of reading-related perceptual expertise. Extending previous research in German, we use a high-density channel array to characterize the N170 topography for reading-related perceptual expertise in English, a language with inconsistent spelling-to-sound mapping. N170 effects related to overall reading-related expertise are defined by contrasting responses to visual words versus novel symbol strings. By contrasting each of these conditions to pseudowords, we examined how this reading-related N170 effect generalizes to well-ordered novel letter strings. A sample-by-sample permutation test computed on word versus symbol ERP topographies revealed differences during two time windows corresponding to the N170 and P300 components. Topographic centroid analysis of the word and symbol N170 demonstrated significant differences in both left-right as well as inferior-superior dimensions. Words elicited larger N170 negativities than symbols at inferior occipito-temporal channels, with the maximal effect over left inferior regions often unsampled in conventional electrode montages. Further contrasts produced inferior-superior topographic effects for the pseudoword-symbol comparison and left-lateralized topographic effects for the word-pseudoword comparison. Fast specialized perception related to reading experience produces an N170 modulation detectable across different EEG systems and different languages. Characterization of such effects may be improved by sampling with greater spatial frequency recordings that sample inferior regions. Unlike in German, reading-related expertise effects in English produced only partial generalization in N170 responses to novel pseudowords. The topographic inferior-superior N170 differences may reflect general perceptual expertise for orthographic strings, as it was found for words and pseudowords across both languages. The topographic left-right N170 difference between words and pseudowords was only found in English, and may suggest that ambiguity in pronunciating novel pseudowords due to inconsistency in spelling-to-sound mapping influences early stages of letter string processing.