AB5 toxins:: structures and inhibitor design
AB5 toxins:: structures and inhibitor design
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DOI：
10.1016/s0959-440x(00)00152-4
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发表时间：
2000-12-01
影响因子：
6.8
通讯作者：
Hol, WGJ
中科院分区：
文献类型：
--
作者：
Fan, EK;Merritt, EA;Hol, WGJ
High-resolution crystal structures of AB(5) toxins in their native form or in complex with a variety of ligands have led to the structure-based design and discovery of inhibitors targeting different areas of the toxins. The most significant progress is the development of highly potent multivalent ligands that block binding of the toxins to their receptors.
