Response selection codes in neurophysiological data predict conjoint effects of controlled and automatic processes during response inhibition
Response selection codes in neurophysiological data predict conjoint effects of controlled and automatic processes during response inhibition
复制标题
DOI：
10.1002/hbm.23974
复制
发表时间：
2018-04-01
影响因子：
4.8
通讯作者：
Beste, Christian
中科院分区：
文献类型：
--
作者：
Chmielewski, Witold X.;Mueckschel, Moritz;Beste, Christian
优势反应的抑制是目标导向行为的必要条件，几个因素决定了相应的成功反应抑制过程。一个因素涉及到的自动化程度的pre-potent的反应倾向和另一个因素涉及到的程度的认知控制，是在反应抑制。然而，这两个因素可以联合调节抑制控制。认知理论的概念表明，编码的刺激反应翻译可能是这种联合效应的基础。然而，目前还不清楚在多大程度上，这些特定的代码，在认知心理学概念中假设，是明显的神经生理过程中，是否有特定的功能神经解剖结构与这些代码的处理。应用EEG数据的时间分解方法结合源定位方法，我们表明存在不同的混合代码（即，“刺激代码”和“反应选择代码”）在反应抑制中的“自动”和“受控”过程的联合作用期间的神经生理学水平上。重要的是，只有“反应选择代码”预测行为表现，并受到“自动”和“控制”过程的联合调制。这些调制与下部和上级顶叶区（BA 40/BA 7），可能反映了更新的内部表示时，信息是复杂的，可能难以分类，但行为控制是必不可少的。由认知和心理学概念提出的代码似乎有一个神经生理学的类似物，符合目前关于顶叶下部和上级区域功能的观点。
The inhibition of prepotent responses is a requirement for goal-directed behavior and several factors determine corresponding successful response inhibition processes. One factor relates to the degree of automaticity of pre-potent response tendencies and another factor relates to the degree of cognitive control that is exerted during response inhibition. However, both factors can conjointly modulate inhibitory control. Cognitive theoretical concepts suggest that codings of stimulus-response translations may underlie such conjoint effects. Yet, it is unclear in how far such specific codes, as assumed in cognitive psychological concepts, are evident in neurophysiological processes and whether there are specific functional neuroanatomical structures associated with the processing of such codes. Applying a temporal decomposition method of EEG data in combination with source localization methods we show that there are different, intermingled codes (i.e., "stimulus codes" and "response selection codes") at the neurophysiological level during conjoint effects of "automatic" and "controlled" processes in response inhibition. Importantly, only "response selection codes" predict behavioral performance, and are subject to conjoint modulations by "automatic" and "controlled" processes. These modulations are associated with inferior and superior parietal areas (BA40/BA7), possibly reflecting an updating of internal representations when information is complex and probably difficult to categorize, but essential for behavioral control. Codes proposed by cognitive, psychological concepts seem to have a neurophysiological analogue that fits into current views on functions of inferior and superior parietal regions.