Comparison of optical quality and distinct macular thickness in femtosecond laser-assisted versus phacoemulsification cataract surgery
Comparison of optical quality and distinct macular thickness in femtosecond laser-assisted versus phacoemulsification cataract surgery
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飞秒激光辅助与超声乳化白内障手术的光学质量和黄斑厚度的比较
DOI：
10.1186/s12886-020-1319-3
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发表时间：
2020-02-01
影响因子：
2
通讯作者：
Guan, Huaijin
中科院分区：
文献类型：
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作者：
Wang, Yong;Zhang, Jinling;Guan, Huaijin
飞秒激光辅助白内障手术（FLACS）后光学质量和黄斑厚度变化的报道很少。在目前的研究中，我们评估了FLACS和超声乳化白内障手术（PCS）后的光学质量恢复和黄斑厚度的明显变化。方法选取100例白内障患者（100眼），其中FLACS组50眼，PCS组50眼。采用射线追踪像差仪（iTrace）测量调制传递函数（MTF）、点扩散函数（PSF）和功能失调透镜指数（DLI）。术前、术后1周和1个月分别评估未矫正距离视力（UDVA）和矫正距离视力（CDVA）。选取空间频率为5、10、15、20、25和30 cycles/degree （c/d）的MTF值。我们采用光学相干断层扫描（OCT）评估术前和术后1个月黄斑不同区域的厚度。结果PCS组术前与术后DLI （p< 0.0001）、PSF (strehl ratio， SR) （p= 0.027）、MTF （p= 0.028）差异均有统计学意义，但眼压（IOP）差异无统计学意义（p= 0.857）。FLACS组术后DLI （p= 0.031）、SR （p= 0.01）、IOP （p= 0.03）差异无统计学意义，MTF （p= 0.128）差异无统计学意义。在空间频率为5、10、25时，PCS组术前与术后差异有统计学意义（p= 0.013、0.031、0.048），而FLACS组1个月时差异无统计学意义。在PCS组中，我们发现术前和术后在1个月时的鼻黄斑间环厚度（NIMRT） （p= 0.03）、中央凹体积（FV） （p= 0.034）和平均视网膜厚度（ART） （p= 0.025）上存在差异，而FLACS组无差异。结论flacs是安全的，在目前的研究中没有引起黄斑厚度的明显增加。然而，它也不能产生更好的光学质量。相比之下，PCS可产生黄斑厚度变化，但光学质量恢复较好。轻微的视网膜变化可能不会影响光学质量。
BackgroundOptical quality and macular thickness changing optical quality is rarely reported after femtosecond laser-assisted cataract surgery (FLACS). In current research, we evaluated optical quality recovery and distinct macular thickness changes after FLACS and phacoemulsification cataract surgery (PCS).MethodsA total of 100 cataract patients (100 eyes) were included (50 eyes for the FLACS group and 50 eyes for the PCS group). Modulation transfer function (MTF), point spread function (PSF) and dysfunctional lens index (DLI) were measured by a ray-tracing aberrometer (iTrace). Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) were also assessed pre-operation,1 week and 1 month after surgery. The MTF values at spatial frequencies of 5, 10, 15, 20, 25 and 30 cycles/degree (c/d) were selected. We used optical coherence tomography (OCT) to assess the macular thickness of different regions pre-operatively and1month after the surgery.ResultsIn PCS group, we found the statistically significant differences between pre-operation and post-operation in DLI (p< 0.0001), PSF (strehl ratio, SR) (p =0.027) and MTF (p= 0.028), but not intraocular pressure (IOP) (p= 0.857). The differences between pre-operation and post-operation for DLI (p= 0.031), SR (p= 0.01) and IOP (p= 0.03), but not MTF (p= 0.128) were also found in FLACS group. The differences were statistically significant when the spatial frequencies were at 5, 10 and 25 (p= 0.013, 0.031 and 0.048) between pre-operation and post-operation in PCS group but not FLACS group at 1 month. In PCS group, we found the differences between pre-operation and post-operation in nasal inter macular ring thickness (NIMRT) (p= 0.03), foveal volume (FV) (p= 0.034) and average retinal thickness (ART) (p= 0.025) but not FLACS group at 1 month.ConclusionFLACS is safe that did not cause significant increase of macular thickness in current study. However, it also cannot produce better optical quality. In contrast, PCS can produce macular thickness changes, but better optical quality recovery. The slightly retinal change may not affect optical quality.