Heterogeneity in ADHD: Neuropsychological Pathways, Comorbidity and Symptom Domains
Heterogeneity in ADHD: Neuropsychological Pathways, Comorbidity and Symptom Domains
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DOI：
10.1007/s10802-008-9286-9
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发表时间：
2009-05-01
影响因子：
3.6
通讯作者：
Bohlin, Gunilla
中科院分区：
文献类型：
--
作者：
Wahlstedt, Cecilia;Thorell, Lisa B.;Bohlin, Gunilla
本研究的目的是调查不同的神经心理障碍和共病的行为问题与注意力缺陷多动障碍（ADHD）的症状，研究不同功能的独立影响，以及多动/冲动和注意力不集中的症状的具体关系。一个以社区为基础的样本的学童（n = 182，ADHD症状范围的高端过采样）完成神经心理学任务，旨在衡量执行功能（EF），状态调节和延迟厌恶。通过父母和教师对ADHD和对立违抗性障碍（ODD）的DSM-IV标准的评分来测量行为症状。分类和维度分析被用来获得更深入的了解ADHD。结果支持了EF和状态调节构成ADHD的独立途径的观点，主要是注意力不集中的症状。此外，本研究还指出了将ADHD视为异质性疾病的重要性，即神经心理功能和合并症对不同ADHD症状组和两个ADHD症状域的不同影响。
The aim of the present study was to investigate different neuropsychological impairments and comorbid behavioral problems in relation to symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD), studying the independent effects of different functions as well as specific relations to symptoms of hyperactivity/impulsivity and inattention. A community-based sample of school children (n = 182; the higher end of the ADHD symptom range was oversampled) completed neuropsychological tasks designed to measure executive function (EF), state regulation and delay aversion. Behavioral symptoms were measured through parental and teacher ratings of the DSM-IV criteria for ADHD and Oppositional Defiant Disorder (ODD). Both categorical and dimensional analyses were used to acquire a deeper understanding of ADHD. The results supported the notion that EF and state regulation constitute independent pathways to ADHD, primarily to symptoms of inattention. In addition, the present study points to the importance of viewing ADHD as a heterogeneous condition also with regard to the differential impact of neuropsychological functioning and comorbidity on different ADHD symptom groups and the two ADHD symptom domains.