Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): predictive factors for functional outcome. Study report no. 6
Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): predictive factors for functional outcome. Study report no. 6
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DOI：
10.1007/s00417-011-1619-7
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发表时间：
2011-08-01
影响因子：
2.7
通讯作者：
Heimann, Heinrich
中科院分区：
文献类型：
--
作者：
Heussen, Nicole;Feltgen, Nicolas;Heimann, Heinrich
目的：探讨对孔源性视网膜脱离（RRD）进行初次玻璃体切除术（PV）和巩膜扣带手术（SB）术后1年最佳矫正视力（BCVA）的相关危险因素。在“随机、前瞻性、多中心临床试验比较巩膜扣带与初次玻璃体切除术修复孔源性视网膜脱离”（SPR研究）中，使用多变量统计方法将1年随访时的最终BCVA与术前和术中结果联系起来。在phakic亚试验中，最终BCVA与断裂次数（p = 0.0259）、症状持续时间（p = 0.0476）、基线BCVA （p = 0.0002）、主要血管拱桥中心的视网膜脱离（p = 0.0088）、完全脱离（p = 0.0027）和断裂链形成（p = 0.0129）相关。在假性晶状体/无晶状体亚试验中，最终BCVA与视网膜断裂次数（p = 0.0010）、继发性白内障或中央囊膜纤维化（p = 0.0141）、术中激光光凝（p = 0.0373）、断裂位于4点钟和8点钟以下的下脱离（p = 0.0173）有关。最终BCVA是RRD手术患者最重要的预后。我们的结果表明，在两个亚试验中，最终的BCVA与术前较高的骨折次数有关。其他危险因素在摄食亚组和假性摄食亚组之间有所不同。
To identify risk factors associated with best-corrected visual acuity (BCVA) 1 year after initial surgery following primary vitrectomy (PV) and scleral buckling surgery (SB) for rhegmatogenous retinal detachment (RRD).Relating the final BCVA at the 1-year follow-up visit to pre- and intraoperative findings in the "randomized, prospective, multicenter clinical trial comparing scleral buckling versus primary vitrectomy for repair of rhegmatogenous retinal detachment" (SPR Study) using multivariate statistical methods.In the phakic subtrial, final BCVA is associated with the number of breaks (p = 0.0259), duration of symptoms (p = 0.0476), baseline BCVA (p = 0.0002), retinal detachment central to major vessels arcades (p = 0.0088), total detachment (p = 0.0027), and chain formation of breaks (p = 0.0129). In the pseudophakic/aphakic subtrial, final BCVA is related to the number of retinal breaks (p = 0.0010), secondary cataract or central capsular fibrosis (p = 0.0141), intraoperative laser photocoagulation (p = 0.0373), and inferior detachment with breaks below the 4 and 8 o'clock positions (p = 0.0173).Final BCVA is the most important outcome for patients undergoing RRD surgery. Our results demonstrate that the final BCVA is related to a higher preoperative number of breaks in both subtrials. Additional risk factors varied between phakic and pseudophakic subgroups.