High dietary ratio of omega-6 to omega-3 polyunsaturated acids during pregnancy and prevalence of post-partum depression
High dietary ratio of omega-6 to omega-3 polyunsaturated acids during pregnancy and prevalence of post-partum depression
复制标题
DOI：
10.1111/j.1740-8709.2010.00256.x
复制
发表时间：
2012-01-01
影响因子：
3.4
通讯作者：
Kac, Gilberto
中科院分区：
文献类型：
--
作者：
da Rocha, Camilla M. M.;Kac, Gilberto
观察性研究表明，低浓度的omega-3家族脂肪酸与产后抑郁症（PPD）的高风险之间存在关联。目的是研究不平衡饮食摄入omega-6/omega-3比例>9:1对PPD患病率的影响。该研究包括一个前瞻性队列，在怀孕期间进行四波随访，分娩后进行一波随访。根据爱丁堡产后抑郁量表（PPD = 11）对2005年至2007年间巴西里约热内卢106例产妇进行PPD评估。独立变量包括社会人口统计学、产科、孕前体重指数（BMI）和饮食摄入数据，这些数据是通过怀孕前三个月的食物频率问卷获得的。统计分析包括PPD患病率计算和多元泊松回归稳健方差。PPD患病率为26.4% [n = 28；可信区间（CI） 95%: 18.034.8]，并且在omega-6/omega-3比值为bb0 9:1（60.0%）的妇女和孕前BMI较高的妇女中观察到PPD的患病率
Observational studies suggest association between low concentrations of omega-3 family fatty acids and greater risk for post-partum depression (PPD). The objective was to investigate the effect of unbalanced dietary intake of omega-6/omega-3 ratio >9:1 in the prevalence for PPD. The study comprises a prospective cohort with four waves of follow-up during pregnancy and one following delivery. PPD was evaluated according to the Edinburgh Post-partum Depression Scale (PPD = 11) in 106 puerperae between 2005 and 2007, in Rio de Janeiro, Brazil. Independent variables included socio-demographic, obstetric, pre-pregnancy body mass index (BMI) and dietary intake data, which were obtained by means of a food frequency questionnaire in the first trimester of pregnancy. Statistical analysis involved calculation of PPD prevalence and multivariate Poisson regression with robust variance. PPD prevalence amounted to 26.4% [n = 28; confidence interval (CI) 95%: 18.034.8], and higher prevalences of PPD were observed in women who consumed an omega-6/omega-3 ratio >9:1 (60.0%) and in those with pre-pregnancy BMI