Spontaneous formation of blood-compatible surfaces on hydrophobic polymers: Surface enrichment of a block copolymer with a water-soluble block
Spontaneous formation of blood-compatible surfaces on hydrophobic polymers: Surface enrichment of a block copolymer with a water-soluble block
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DOI：
10.1002/adma.200500945
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发表时间：
2005-10-04
影响因子：
29.4
通讯作者：
Yokoyama, H
中科院分区：
文献类型：
--
作者：
Oyane, A;Ishizone, T;Yokoyama, H
通过嵌段共聚物的自发表面分离，产生了具有优异血液相容性的聚合物表面。水溶性聚合物嵌段 (PME3MA) 自发分离到疏水和亲水环境中（见图），导致嵌段通过灵活的链运动排出包括蛋白质、细胞和血小板在内的生物物质。
A polymer surface with excellent blood compatibility has been produced via spontaneous surface segregation of a block copolymer. The water-soluble polymer block (PME3MA) spontaneously segregates into hydrophobic and hydrophilic environments (see Figure), causing the blocks to expel biological substances including proteins, cells and platelets via flexible chain motion.