Serum level of immunosuppressive acidic protein in haemodialysis patients with or without renal cell carcinoma.
Serum level of immunosuppressive acidic protein in haemodialysis patients with or without renal cell carcinoma.
复制标题
患有或不患有肾细胞癌的血液透析患者的血清免疫抑制酸性蛋白水平。
DOI：
10.1111/j.1464-410x.1994.tb07595.x
复制
发表时间：
1994
期刊：
影响因子：
--
通讯作者：
T. Sawamura
中科院分区：
文献类型：
--
作者：
I. Sasagawa;T. Nakada;Y. Kubota;H. Suzuki;T. Sawamura
目的
目的探讨免疫抑制酸性蛋白（IAP）在血液透析患者肾癌诊断中的意义。
患者和方法
对74例血液透析患者（其中10例有肾癌，64例无肾癌）的血清IAP和肌酐浓度进行了测定。对照数据来自13名健康献血者。
结果
血液透析患者血清IAP水平显著高于对照组。接受血液透析的肾细胞癌患者的血清IAP水平也显著高于非肾细胞癌患者。肾细胞癌患者与非肾细胞癌患者的血清肌酐水平无显著差异，但与对照组相比，血清肌酐水平显著升高。
结论
血清IAP浓度的测定对血液透析患者肾癌的诊断有一定价值。
OBJECTIVE
To assess the significance of immunosuppressive acidic protein (IAP) for detection of renal cell carcinoma in patients undergoing haemodialysis.
PATIENTS AND METHODS
The serum concentration of both IAP and creatinine was measured in 74 patients undergoing haemodialysis, 10 of whom had renal cell carcinoma and 64 of whom had no renal cell carcinoma. Control data was obtained from 13 healthy blood donors.
RESULTS
The serum IAP level of patients undergoing haemodialysis was significantly elevated compared with that of the controls. The serum level of IAP in patients with renal cell carcinoma who were undergoing haemodialysis was also considerably higher than that of patients with no renal cell carcinoma. The serum creatinine levels were not significantly different between patients with and without renal cell carcinoma but were significantly elevated when compared with the controls.
CONCLUSION
The measurement of serum IAP concentration is of value in the detection of renal cell carcinoma in patients undergoing haemodialysis.