EPIDEMIC TYPHUS RICKETTSIAE ISOLATED FROM FLYING SQUIRRELS
EPIDEMIC TYPHUS RICKETTSIAE ISOLATED FROM FLYING SQUIRRELS
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DOI：
10.1038/255545a0
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发表时间：
1975-01-01
期刊：
影响因子：
64.8
通讯作者：
ELISBERG, BL
中科院分区：
文献类型：
--
作者：
BOZEMAN, FM;MASIELLO, SA;ELISBERG, BL
流行性斑疹伤寒是一种严重的立克次体感染，典型地只涉及人和他的体虱。虽然病原体普氏立克次体已从埃塞俄比亚和埃塞俄比亚的家畜蜱和牲畜血液中分离出来1，2，但这些不寻常的宿主和媒介的感染被认为是继发于虱传疾病在人群中的活跃传播3。奥姆斯比的结论是，牲畜和相当的野生物种在流行性斑疹伤寒的生态学中不太可能是重要的。该病最后一次报告于1836年在美国东部的费城（参考文献5）。我们已经分离出六株R.来自东方飞鼠（Glaucomys volans volans）的prowazekii。这一发现表明，一种非人类的流行性斑疹伤寒宿主可以存在于一种野生啮齿动物中，而与最近发生的流行性或散发性疾病无关。
EPIDEMIC typhus is a severe rickettsial infection that classically has involved only man and his body louse. Although the aetiological agent,Rickettsia prowazekii, has been isolated from ticks of domestic animals and from blood of livestock in Ethiopia and Egypt1,2, infection of these unusual hosts and vectors has been thought to be secondary to active dissemination of the louse-borne disease in the human population3. Ormsbee concluded that livestock and the equivalent wild species were unlikely to be important in the ecology of epidemic typhus4. This disease was last reported in the eastern United States in Philadelphia in 1836 (ref. 5). We have now isolated six strains ofR. prowazekiifrom the eastern flying squirrel (Glaucomys volans volans). This finding suggests that an extrahuman reservoir of epidemic typhus can exist in a species of wild rodent independent of the recent occurrence of epidemic or sporadic disease.