Processing of plant microRNA precursors
Processing of plant microRNA precursors
复制标题
DOI：
10.1093/bfgp/els050
复制
发表时间：
2013-01-01
影响因子：
4
通讯作者：
Palatnik, Javier F.
中科院分区：
文献类型：
--
作者：
Bologna, Nicolas G.;Schapire, Arnaldo L.;Palatnik, Javier F.
MicroRNA 是内源性小 RNA，已知是动物和植物基因表达的关键调节因子。它们是由其特定的生物发生来定义的，其中涉及从不完美的折回前体中精确切除。这些前体含有正确加工所需的结构决定因素。尽管如此，植物和动物 microRNA 的生物发生和活性仍存在显着差异。这篇综述总结了植物前体加工的各个方面，并将其与动物对应物进行了对比。
MicroRNAs are endogenous small RNAs known to be key regulators of gene expression in animals and plants. They are defined by their specific biogenesis which involves the precise excision from an imperfect fold-back precursor. These precursors contain structural determinants required for their correct processing. Still, there are significant differences in the biogenesis and activities of plant and animal microRNAs. This review summarizes diverse aspects of precursor processing in plants, contrasting them to their animal counterparts.