Precision Medicine in Low- and Middle-Income Countries.

Precision Medicine in Low- and Middle-Income Countries.
复制标题

DOI:
10.1146/annurev-pathol-042320-034052
复制
发表时间:
2022-01-24
期刊:
Annual review of pathology
影响因子:
--
通讯作者:
--
中科院分区:
其他
文献类型:
--
作者:

文献摘要

参考文献

被引文献

相似文献

大多数癌症病例发生在低收入和中等收入国家(LMIC)。在富裕国家,癌症的最佳诊断、治疗和监测所需的先进技术和人力基础设施已经很困难;在中低收入国家,这尤其具有挑战性。在西方,受过教育的,工业化的,富裕的,民主的国家,越来越重视和成功的精准医学,其中靶向治疗是针对癌症的特定基因病变的癌症。在中低收入国家能否提供这种精确的方法?我们提供了一些新颖的合作伙伴关系和创造性解决方案的例子,这些例子表明,如果有大量的意愿、创造力、毅力和一点运气,精准医疗在中低收入国家是可能的。
Most cancer cases occur in low- and middle-income countries (LMICs). The sophisticated technical and human infrastructure needed for optimal diagnosis, treatment, and monitoring of cancers is difficult enough in affluent countries; it is especially challenging in LMICs. In Western, educated, industrial, rich, democratic countries, there is a growing emphasis on and success with precision medicine, whereby targeted therapy is directed at cancers based on the specific genetic lesions in the cancer. Can such precision approaches be delivered in LMICs? We offer some examples of novel partnerships and creative solutions that suggest that precision medicine may be possible in LMICs given heavy doses of will, creativity, and persistence and a little luck.
DOI: 10.1158/1055-9965.epi-15-0535
发表时间: 2015-10-01
影响因子: 3.8
作者:
DeSantis, Carol E.;Bray, Freddie;Jemal, Ahmedin
通讯作者: Jemal, Ahmedin
DOI: 10.1245/s10434-008-9900-7
发表时间: 2008-07-01
影响因子: 3.7
作者:
Bird, P. A.;Hill, A. G.;Houssami, N.
通讯作者: Houssami, N.
DOI: 10.2353/jmoldx.2007.060112
发表时间: 2007-04-01
影响因子: 4.1
作者:
Jobbagy, Zsolt;van Atta, Reuel;Gocke, Christopher D.
通讯作者: Gocke, Christopher D.
DOI: 10.1016/s0140-6736(18)32984-2
发表时间: 2019-01-19
期刊: LANCET
影响因子: 168.9
作者:
Horwitz, Steven;O'Connor, Owen A.;Zinzan, Pier Luigi
通讯作者: Zinzan, Pier Luigi
DOI: 10.3389/fonc.2018.00346
发表时间: 2018
影响因子: 4.7
作者:
Drake TM;Knight SR;Harrison EM;Søreide K
通讯作者: Søreide K