Biodegradable Smart Nanogels: A New Platform for Targeting Drug Delivery and Biomedical Diagnostics
Biodegradable Smart Nanogels: A New Platform for Targeting Drug Delivery and Biomedical Diagnostics
复制标题
可生物降解的智能纳米凝胶：靶向药物输送和生物医学诊断的新平台
DOI：
10.1021/acs.langmuir.6b00842
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发表时间：
2016
期刊：
影响因子：
3.9
通讯作者：
Wang Chang-Chun
中科院分区：
文献类型：
--
作者：
Wu Hai-Qiu;Wang Chang-Chun
Nanogels (or nanohydrogels) have been extensively investigated as one of the most promising nanoparticulate biomedical platforms owing to their advantageous properties that combine the characteristics of hydrogel systems with nanoparticles. Among them, smart nanogels that have the ability to respond to external stimuli, such as pH, redox, temperature, enzymes, light, magnetic field and so forth, are most attractive in the area of drug delivery. Besides, numerous multifunctionalized nanogels with high sensitivity and specificity were designed for diagnostic applications. In this feature article, we have reviewed and discussed the recent progress of biodegradable nanogels as smart nanocarriers of anticancer drugs and biomedical diagnostic agents for cancer.
