Michigan Molecular Interactions (MiMI): putting the jigsaw puzzle together.
Michigan Molecular Interactions (MiMI): putting the jigsaw puzzle together.
复制标题
密歇根分子相互作用（MIMI）：将拼图拼图放在一起。
DOI：
10.1093/nar/gkl859
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发表时间：
2007-01
影响因子：
14.9
通讯作者：
中科院分区：
文献类型：
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作者：
蛋白质相互作用数据存在于许多存储库中。每个储存库都有自己的数据格式、分子标识符和补充信息。Michigan Molecular Interactions（MiMI）帮助科学家搜索大量的蛋白质相互作用数据。MiMI从知名的蛋白质相互作用数据库中收集数据，并对信息进行深度合并。利用同一性函数，可以合并可能具有不同标识符但代表相同现实世界对象的分子。因此，MiMI允许用户同时从许多不同的数据库中检索信息，突出互补和矛盾的信息。为了帮助科学家判断数据的有用性，MiMI跟踪所有数据的来源。最后，一个简单而强大的用户界面帮助用户进行查询，并将他们从了解数据格式或学习查询语言的繁重任务中解放出来。MiMI允许科学家查询所有数据，无论是确证的还是矛盾的，并指定使用哪些来源。MiMI是国家综合生物医学信息学中心（NCIBI）的一部分，可在以下网址公开获取：。
Protein interaction data exists in a number of repositories. Each repository has its own data format, molecule identifier and supplementary information. Michigan Molecular Interactions (MiMI) assists scientists searching through this overwhelming amount of protein interaction data. MiMI gathers data from well-known protein interaction databases and deep-merges the information. Utilizing an identity function, molecules that may have different identifiers but represent the same real-world object are merged. Thus, MiMI allows the users to retrieve information from many different databases at once, highlighting complementary and contradictory information. To help scientists judge the usefulness of a piece of data, MiMI tracks the provenance of all data. Finally, a simple yet powerful user interface aids users in their queries, and frees them from the onerous task of knowing the data format or learning a query language. MiMI allows scientists to query all data, whether corroborative or contradictory, and specify which sources to utilize. MiMI is part of the National Center for Integrative Biomedical Informatics (NCIBI) and is publicly available at: .