Chemotaxis of a model organism: progress with Dictyostelium.
Chemotaxis of a model organism: progress with Dictyostelium.
复制标题
模型生物的趋化性:盘基网柄菌的进展。
DOI:
10.1016/j.ceb.2015.06.005
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发表时间:
2015
影响因子:
7.5
通讯作者:
Nichols JM
中科院分区:
文献类型:
--
作者:
Nichols JM
Model organisms have been key to understanding many core biological processes. Dictyostelium amoebae have the attributes required to perform this role for chemotaxis, and by providing an evolutionary distant reference point to mammalian cells, they allow the central features of chemotaxis to be discerned. Here we highlight progress withDictyosteliumin understanding: pseudopod and bleb driven movement; the role of the actin cytoskeleton; chemotactic signal processing, including how cells adapt to background stimulation, and the controversial role of PIP3. Macropinocytosis and the axenic mutations are raised as potential confounding factors, while the identification of new players through proteomics holds great promise.
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影响因子:
3.3
作者:
Para,Alessia;Krischke,Miriam;Merlot,Sylvain;Shen,Zhouxin;Oberholzer,Michael;Lee,Susan;Briggs,Steven;Firtel,RichardA
通讯作者:
Firtel,RichardA
影响因子:
64.8
作者:
Dang, Irene;Gorelik, Roman;Gautreau, Alexis
通讯作者:
Gautreau, Alexis
影响因子:
3.3
作者:
Sugden C;Urbaniak MD;Araki T;Williams JG
通讯作者:
Williams JG
DOI:
10.1083/jcb.201205058
发表时间:
2012-08-20
期刊:
The Journal of cell biology
影响因子:
--
作者:
Veltman DM;King JS;Machesky LM;Insall RH
通讯作者:
Insall RH
DOI:
--
发表时间:
1985
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Devreotes,PN;Sherring,JA
通讯作者:
Sherring,JA