Mortality study of British pathologists 1974-80.
Mortality study of British pathologists 1974-80.
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英国病理学家 1974-80 年死亡率研究。
DOI：
10.1136/oem.41.2.188
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
D. Oakes
中科院分区：
文献类型：
--
作者：
J. Harrington;D. Oakes
成员名单的皇家学院的病理学家从1974年至1980年被用来建立一个人口的2307名男性和413名女性。在研究期间，这些病理学家中有126人死亡，并获得了121人的死亡证明。所有原因的标准化死亡率（SMR）男性为56，女性为99。意外事故、中毒、暴力，特别是自杀造成的死亡人数超过了一般人口的预期，但与医生的死亡人数相似。吸毒过量是每一次自杀的原因。在以前的研究中没有发现淋巴和造血系统肿瘤造成的过多死亡，但发现了脑肿瘤造成的过多死亡，包括迄今收集的1981年数据，脑肿瘤造成的死亡显然过多（观察到6例，预期小于2.0，p小于0.02）。可能的病因学假设包括既往接触有机溶剂或结核感染。鉴于病理学家暴露于甲醛，值得注意的是，没有报告鼻或鼻窦肿瘤，肺癌的SMR为41。
Membership lists of the Royal College of Pathologists from 1974 to 1980 were used to establish a population of 2307 men and 413 women. During the period of study 126 of these pathologists died and death certificates were obtained for 121. The standardised mortality ratios (SMR) for all causes in men were 56 and in women 99. Deaths from accidents, poisoning, violence, and especially suicide, were noted to be in excess of that expected from the general population but similar to that for medical practitioners. Drug overdose was the cause of each suicide. Excess deaths from lymphatic and haemopoietic neoplasms noted in a previous study were not present but an excess of brain tumours was found. Including 1981 data thus far collected, deaths from brain tumour were apparently in excess (observed 6, expected less than 2.0, p less than 0.02). Possible aetiological hypotheses include previous exposure to organic solvents or tuberculosis infection. In view of the pathologists' exposure to formaldehyde it is interesting to note that no nasal or nasal sinus tumours were reported and the SMR for lung cancer was 41.