THE FILTRATION CHARACTERISTICS OF THE AQUEOUS OUTFLOW SYSTEM
THE FILTRATION CHARACTERISTICS OF THE AQUEOUS OUTFLOW SYSTEM
复制标题
DOI：
10.1016/0014-4835(90)90142-h
复制
发表时间：
1990-04-01
影响因子：
3.4
通讯作者：
EPSTEIN, DL
中科院分区：
文献类型：
--
作者：
JOHNSON, M;JOHNSON, DH;EPSTEIN, DL
为了确定水流出系统的过滤特性，将微球(0.18微米-1.1微米)通过去核的人和牛眼灌流。微球比形态确定的流动尺寸小，但捕获了所有尺寸的微球的很大一部分。牛(小牛)房水流出系统被发现是一个比人类流出系统更有效的过滤器。将实验结果与形态观察和理论计算相结合，得出了微球捕获的主要原因是“粘壁”相互作用的结论，并且过滤位置可能与流动阻力的位置不同。因此，产生流动阻力的部位的尺寸不能从过滤研究中确定。
To determine the filtration characteristics of the aqueous outflow system, microspheres (0.18 .mu.m-1.1 .mu.m) were perfused through enucleated human and bovine eyes. The microspheres were smaller than morphologically determined flow dimensions, and yet a significant fraction of all sizes of microspheres were captured. The bovine (calf) aqueous outflow system was found to be a far more efficient filter than was the human outflow system. Combining the experimental results with morphological observations and theoretical calculations leads to the conclusion that ''sticky wall'' interactions are responsible for much of the microsphere capture, and that the site of filtration may be distinct from the site of flow resistance. Consequently, the dimension of the sites generating flow resistance cannot be determined from filtration studies.