Topographical organization of human corpus callosum: An fMRI mapping study
Topographical organization of human corpus callosum: An fMRI mapping study
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DOI：
10.1016/j.brainres.2010.11.039
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发表时间：
2011-01-25
期刊：
影响因子：
2.9
通讯作者：
Manzoni, Tullio
中科院分区：
文献类型：
--
作者：
Fabri, Mara;Polonara, Gabriele;Manzoni, Tullio
胼胝体 (CC) 地形图的概念源自人类病变研究和其他哺乳动物的解剖追踪研究。在过去的几年里，越来越多的研究人员报告了白质（尤其是 CC）的功能磁共振成像 (fMRI) 激活。在这项研究中，通过简单的感觉刺激和运动任务诱发激活，探索了用功能磁共振成像描述 CC 地形的范围。我们回顾了从 36 名志愿者身上获得的已发表和未发表的关于触觉、味觉、视觉敏感性和运动激活的皮质表征的功能磁共振成像数据。在离散的 CC 区域中一致检测到激活灶：前部（味觉刺激）、中枢（运动任务）、中枢和后部（触觉刺激）以及压部（视觉刺激）。这些发现表明，可以通过功能磁共振成像来探索 CC 的功能拓扑。 (C) 2010 Elsevier B.V. 保留所有权利。
The concept of a topographical map of the corpus callosum (CC) has emerged from human lesion studies and from anatomical tracing investigations in other mammals. Over the last few years, a rising number of researchers have been reporting functional magnetic resonance imaging (fMRI) activation in white matter, particularly the CC. In this study, the scope for describing CC topography with fMRI was explored by evoking activation through simple sensory stimulation and motor tasks. We reviewed our published and unpublished fMRI data on the cortical representation of tactile, gustatory, and visual sensitivity and of motor activation, obtained in 36 volunteers. Activation foci were consistently detected in discrete CC regions: anterior (taste stimuli), central (motor tasks), central and posterior (tactile stimuli), and splenium (visual stimuli). These findings demonstrate that the functional topography of the CC can be explored with fMRI. (C) 2010 Elsevier B.V. All rights reserved.