SYSTEM-DESIGN OF FAST PET SCANNERS UTILIZING TIME-OF-FLIGHT
SYSTEM-DESIGN OF FAST PET SCANNERS UTILIZING TIME-OF-FLIGHT
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DOI：
10.1109/tns.1981.4331148
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发表时间：
1981-01-01
影响因子：
1.8
通讯作者：
WONG, G
中科院分区：
文献类型：
--
作者：
MULLANI, NA;FICKE, DC;WONG, G
PET设计的最新进展表明，通过在常规PET模式上将飞行时间数据并入正电子发射断层扫描中，可以预期信噪比的增益。还已经表明，氟化铯（CsF）提供了利用飞行时间信息的临床扫描仪所需的更快计时和高检测效率的潜力。我们的研究与CsF和时间关光正电子发射断层扫描重建的可行性研究的结果表明，确实，从这样的方法，图像质量的结果显着改善，符合解决时间小于500皮秒半高宽很容易实现与CsF探测器。然而，设计具有多个检测器的快速层析成像系统，保持这种快速符合定时，提出了一个具有挑战性的技术问题。这个问题的解决方案需要从PET设计的常规模式转向基于快速在线微处理器的系统，该系统能够压缩和校正数据的定时差、标准化和图像功能。本文介绍了这种系统，并讨论了它的优点和缺点。
Recent advances in PET designs have shown that a gain in signal-to-noise ratio can be expected by incorporating time-of-flight data in positron emission tomography over the conventional PET mode. It has also been shown that cesium fluoride (CsF) offers the potential of faster timing and high detection efficiency which would be required for a clinical scanner utilizing time-of-flight information. Our research with CsF and the results of a feasibility study of time-off-light positron emission tomography reconstruction have shown that, indeed, a significant improvement in image quality results from such an approach and that coincidence resolving times of less than 500 psec FWHM are easily achievable with CsF detectors. However, the design of fast tomographic systems with multiple detectors which maintain this fast coincidence timing poses a challenging technical problem. The solution to this problem requires a departure from the conventional mode of PET designs to a fast on-line microprocessor based system which is capable of compressing and correcting the data for timing differences, normalization and image function. Such a system is described in this paper and its advantages and disadvantages are discussed.