A new picornavirus isolated from bank voles (Clethrionomys glareolus)

A new picornavirus isolated from bank voles (Clethrionomys glareolus)
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DOI:
10.1006/viro.1998.9557
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发表时间:
1999-03-01
期刊:
影响因子:
3.7
通讯作者:
Winberg, G
Winberg, G
中科院分区:
医学3区
文献类型:
--
作者:
Niklasson, B;Kinnunen, L;Winberg, G

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一种以前未知的小核糖核酸病毒分离银行票(Clethrionomys glareolus)。电子显微镜图像和原型分离物的序列数据,命名为Ljungan病毒,表明它是一种小核糖核酸病毒。预测的Ljungan病毒衣壳蛋白VP2和VP3的氨基酸序列与人类病原体埃可病毒22密切相关(约70%的相似性)。Ljungan病毒的部分5'非编码区序列显示与心脏病毒的相关性最高。另外两个分离株在血清学和分子学上与原型相关。(C)北京:科学出版社.
A previously unknown picornavirus was isolated from bank votes (Clethrionomys glareolus). Electron microscopy images and sequence data of the prototype isolate, named Ljungan virus, showed that it is a picornavirus. The amino acid sequences of predicted Ljungan virus capsid proteins VP2 and VP3 were closely related to the human pathogen echovirus 22 (approximately 70% similarity). A partial 5' noncoding-region sequence of Ljungan virus showed the highest degree of relatedness to cardioviruses. Two additional isolates were serologically and molecularly related to the prototype. (C) 1999 Academic Press.