2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.
2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.
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DOI：
10.1002/art.38098
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发表时间：
2013-11
影响因子：
--
通讯作者：
Pope, Janet E.
中科院分区：
文献类型：
--
作者：
van den Hoogen, Frank;Khanna, Dinesh;Fransen, Jaap;Johnson, Sindhu R.;Baron, Murray;Tyndall, Alan;Matucci-Cerinic, Marco;Naden, Raymond P.;Medsger, Thomas A., Jr.;Carreira, Patricia E.;Riemekasten, Gabriela;Clements, Philip J.;Denton, Christopher P.;Distler, Oliver;Allanore, Yannick;Furst, Daniel E.;Gabrielli, Armando;Mayes, Maureen D.;van Laar, Jacob M.;Seibold, James R.;Czirjak, Laszlo;Steen, Virginia D.;Inanc, Murat;Kowal-Bielecka, Otylia;Mueller-Ladner, Ulf;Valentini, Gabriele;Veale, Douglas J.;Vonk, Madelon C.;Walker, Ulrich A.;Chung, Lorinda;Collier, David H.;Csuka, Mary Ellen;Fessler, Barri J.;Guiducci, Serena;Herrick, Ariane;Hsu, Vivien M.;Jimenez, Sergio;Kahaleh, Bashar;Merkel, Peter A.;Sierakowski, Stanislav;Silver, Richard M.;Simms, Robert W.;Varga, John;Pope, Janet E.
1980年的系统性硬化症分类标准对早期系统性硬化症和局限性皮肤硬化症缺乏敏感性。成立了一个ACR-EULAR联合委员会，为SSC制定新的分类标准。采用共识方法，将23个候选条目排列在多准则加分系统中，并设定阈值将病例归类为SSC。通过对项目进行聚类，简化权重，简化了分类体系。该系统通过以下方式进行测试：a)确定SSc病例和患有硬皮病样疾病的对照的特异性和敏感性；b)对照一组专家对患有或不患有SSc的病例的综合观点进行验证。延伸到MCP近端的手指皮肤增厚足以被归类为SSC，如果不存在SSC，则适用七个附加项目，每个项目的权重不同：手指皮肤增厚、指尖病变、毛细血管扩张、甲皱毛细血管异常、间质性肺疾病或肺动脉高压、雷诺氏现象和SSC相关自身抗体。在验证样本中，新分类标准的敏感性和特异性分别为0.91和0.92,1980年ARA分类标准的敏感性和特异性分别为0.75和0.72。所有选定的案例都根据基于协商一致的专家意见进行了分类。所有被1980年ARA标准归类为SSC的病例都用新的标准分类，现在又有几个病例被认为是SSC。ACR-EULAR的SSC分类标准比1980年ARA的SSSC标准表现更好，应该允许更多的患者被正确地归类为SSC。
The 1980 classification criteria for systemic sclerosis (SSc) lack sensitivity in early SSc and limited cutaneous SSc. A joint ACR-EULAR committee was established to develop new classification criteria for SSc. Using consensus methods, 23 candidate items were arranged in a multi-criteria additive point system with a threshold to classify cases as SSc. The classification system was reduced by clustering items, and simplifying weights. The system was tested by: a) determining specificity and sensitivity in SSc cases and controls with scleroderma-like disorders; b) validating against the combined view of a group of experts on a set of cases with or without SSc. Skin thickening of the fingers extending proximal to the MCPs is sufficient to be classified as SSc, if that is not present, seven additive items apply with varying weights for each: skin thickening of the fingers, finger tip lesions, telangiectasia, abnormal nailfold capillaries, interstitial lung disease or pulmonary arterial hypertension, Raynaud's phenomenon, and SSc-related autoantibodies. Sensitivity and specificity in the validation sample were 0.91 and 0.92 for the new classification criteria and 0.75 and 0.72 for the 1980 ARA classification criteria. All selected cases were classified in accordance with consensus-based expert opinion. All cases classified as SSc by the 1980 ARA criteria were classified with the new criteria, and several additional cases were now considered to be SSc. The ACR-EULAR classification criteria for SSc performed better than the 1980 ARA Criteria for SSc and should allow for more patients to be classified correctly as SSc.
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影响因子：
4.7
作者：
Fransen, Jaap;Johnson, Sindhu R.;Khanna, Dinesh
通讯作者：
Khanna, Dinesh
影响因子：
3.4
作者：
Baron, Murray;Bell, Mary;Taillefer, Suzanne
通讯作者：
Taillefer, Suzanne
影响因子：
--
作者：
Koenig, Martial;Joyal, France;Senecal, Jean-Luc
通讯作者：
Senecal, Jean-Luc
影响因子：
5.9
作者：
HARPER, FE;MARICQ, HR;LEROY, EC
通讯作者：
LEROY, EC
影响因子：
4.7
作者：
Johnson, Sindhu R.;Fransen, Jaap;Pope, Janet E.
通讯作者：
Pope, Janet E.