Recent progress in multiple sequence alignment: a survey

Recent progress in multiple sequence alignment: a survey
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DOI:
10.1517/14622416.3.1.131
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发表时间:
2002-01-01
期刊:
影响因子:
2.1
通讯作者:
Notredame, C
Notredame, C
中科院分区:
医学4区
文献类型:
--
作者:
Notredame, C

文献摘要

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多序列比对(MSA)的组装已经成为处理序列分析时最常见的任务之一。不幸的是,广泛的可用方法和这些方法给出的结果的差异使得非专家很难决定哪个程序最适合给定的目的。在这篇评论中,我们简要介绍了现有的技术,并揭示了最广泛使用的多对齐包的潜在优势和劣势。
The assembly of a multiple sequence alignment (MSA) has become one of the most common tasks when dealing with sequence analysis. Unfortunately, the wide range of available methods and the differences in the results given by these methods makes it hard for a non-specialist to decide which program is best suited for a given purpose. In this review we briefly describe existing techniques and expose the potential strengths and weaknesses of the most widely used multiple alignment packages.