A retrospective observational study to assess adverse transfusion reactions of patients with and without prior transfusion history
A retrospective observational study to assess adverse transfusion reactions of patients with and without prior transfusion history
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DOI：
10.1111/vox.12208
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发表时间：
2015-04-01
期刊：
影响因子：
2.7
通讯作者：
Takamoto, S.
中科院分区：
文献类型：
--
作者：
Kato, H.;Nakayama, T.;Takamoto, S.
背景和目的本研究比较了第一次输血后不良输血反应（ATR）的频率与随后（非第一次）transfuses.Materials和MethodsFive医院同意系统地收集和共享20年的数据。这是一个回顾性的观察分析的数据，包括输血事件和ATR的红细胞（RBC），新鲜冷冻血浆（FFP）和血小板浓缩物（PC）的数量首次输血收件人和以前transfused.ResultsFirst输血ATR红细胞，FFP和PC分别为108%，284%和334%。这些高于随后输血时RBC（069%）、FFP（191%）和PC（275%）的ATR发生率。具体而言，第一次输血的发生率发热非溶血性输血反应（FNHTRs）红细胞（043%）和过敏反应FFP（251%）高于随后的transfuses（红细胞：023%，FFP：165%）。
Background and ObjectivesThis study compares the frequency of adverse transfusion reactions (ATRs) after first transfusions with the frequency of ATRs for subsequent (non-first) transfusions.Materials and MethodsFive hospitals agreed to systematically collect and share 2years of data. This was a retrospective observational analysis of data including the number of transfusion episodes and ATRs for red blood cells (RBCs), fresh frozen plasma (FFP) and platelet concentrates (PCs) given to first-time transfusion recipients and to those previously transfused.ResultsFirst transfusion ATRs to RBCs, FFP and PCs were 108%, 284% and 334%, respectively. These are higher than ATR incidences to RBCs (069%), FFP (191%) and PCs (275%) on subsequent transfusions. Specifically, first transfusion incidences of febrile non-haemolytic transfusion reactions (FNHTRs) to RBCs (043%) and allergic reactions to FFP (251%) were higher than on subsequent transfusions (RBCs: 023%, FFP: 165%).ConclusionThere are risks of ATRs on the first transfusion as well as transfusions of patients with transfusion history.