Dermoscopy of pigmented lesions on mucocutaneous junction and mucous membrane
Dermoscopy of pigmented lesions on mucocutaneous junction and mucous membrane
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DOI：
10.1111/j.1365-2133.2009.09251.x
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发表时间：
2009-12-01
影响因子：
10.3
通讯作者：
Saida, T.
中科院分区：
文献类型：
--
作者：
Lin, J.;Koga, H.;Saida, T.
P>背景皮肤粘膜交界处和粘膜上的色素性病变的皮肤镜特征与多毛皮肤上的色素性病变不同。良性病变和恶性黑色素瘤的这些网站之间的区分往往是difficul. Objective. ObjectiveDermoscopic模式的病变上的mucocutaneous交界处和粘膜，并评估标准dermoscopic算法的适用性，这些lessons.Patients和methodsAn连续系列的40个病变上的mucocutaneous交界处和粘膜进行了研究。所有的病变成像使用皮肤镜设备，分析皮肤镜模式和评分的算法，包括ABCD规则，孟席斯法，7点检查表，3点检查表和CASH algorithm. ResultsBenignpigmented病变的粘膜皮肤交界处和粘膜经常提出了一个点状，球状图案（25%），均匀图案（25%），鱼鳞样（18个中心点，8%）和菌丝样（18个中心点，8%），而这些部位的黑色素瘤表现为多成分型（75%）和均匀型（25%）。鱼鳞状和菌丝状被认为是环状的变体。ABCD规则、Menzies法、7点检查表、3点检查表和CASH算法诊断粘膜黑色素瘤的敏感性分别为100%、100%、63%、88%和100%;特异性分别为100%、94%、100%、94%和100%，结论粘膜黑斑病斑以环状及变异型（鱼鳞样、菌丝样）、点球状及均质型多见。多毛皮肤上色素性病变的算法也适用于粘膜皮肤交界处和粘膜上的色素性病变，具有高灵敏度和特异性。
P>BackgroundThe dermoscopic features of pigmented lesions on the mucocutaneous junction and mucous membrane are different from those on hairy skin. Differentiation between benign lesions and malignant melanomas of these sites is often difficult.ObjectiveTo define the dermoscopic patterns of lesions on the mucocutaneous junction and mucous membrane, and assess the applicability of standard dermoscopic algorithms to these lesions.Patients and methodsAn unselected consecutive series of 40 lesions on the mucocutaneous junction and mucous membrane was studied. All the lesions were imaged using dermoscopy devices, analysed for dermoscopic patterns and scored with algorithms including the ABCD rule, Menzies method, 7-point checklist, 3-point checklist and the CASH algorithm.ResultsBenign pigmented lesions of the mucocutaneous junction and mucous membrane frequently presented a dotted-globular pattern (25%), a homogeneous pattern (25%), a fish scale-like pattern (18 center dot 8%) and a hyphal pattern (18 center dot 8%), while melanomas of these sites showed a multicomponent pattern (75%) and a homogeneous pattern (25%). The fish scale-like pattern and hyphal pattern were considered to be variants of the ring-like pattern. The sensitivities of the ABCD rule, Menzies method, 7-point checklist, 3-point checklist and CASH algorithm in diagnosing mucosal melanomas were 100%, 100%, 63%, 88% and 100%; and the specificities were 100%, 94%, 100%, 94% and 100%, respectively.ConclusionThe ring-like pattern and its variants (fish scale-like pattern and hyphal pattern) are frequently observed as well as the dotted-globular pattern and homogeneous pattern in mucosal melanotic macules. The algorithms for pigmented lesions on hairy skin also apply to those on the mucocutaneous junction and mucous membrane with high sensitivity and specificity.