Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces
Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces
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DOI：
10.4012/dmj.2012-061
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发表时间：
2012-11-01
影响因子：
2.5
通讯作者：
Nakano, Takayoshi
中科院分区：
文献类型：
--
作者：
Ma, Sai;Imazato, Satoshi;Nakano, Takayoshi
本研究的目的是评估含有表面预反应玻璃离聚物 (S-PRG) 填料的涂层材料在体外保护牙根免于脱矿质的能力。将含有 S-PRG 填充剂的专有涂层树脂（PRG Barrier Coat）涂在人根牙本质上，并浸入 pH 4.5 的酸性缓冲液中 3 d。通过显微 CT 扫描评估脱矿情况，并通过扫描电子显微镜观察牙本质-材料界面。通过使用离子敏感场效应晶体管 pH 电极监测 pH 值，研究了涂层树脂改变变形链球菌产酸的能力。 PRG Barrier Coat 的应用产生了厚度约为 200 p,m 的涂层，完全抑制了脱矿质。细菌引起的材料表面pH值下降被显着抑制。我们得出的结论是，含 S-PRG 填料的涂层树脂可能是保护暴露的根部免受化学和生物挑战的有效材料。
The purpose of this study was to evaluate the ability of a coating material containing the surface pre-reacted glass-ionomer (S-PRG) filler to protect the root from demineralization in vitro. The proprietary coating resin containing the S-PRG filler (PRG Barrier Coat) was applied to human root dentin and immersed in acid buffer at pH 4.5 for 3 d. Demineralization was evaluated by micro-CT scanning and the dentin-material interface observed by scanning electron microscopy. The ability of the coating resin to modify acid production by Streptococcus mutans was investigated by monitoring pH using an ion-sensitive field-effect transistor pH electrode. Application of PRG Barrier Coat produced a coating layer with the thickness of approximately 200 p,m and completely inhibited demineralization. The bacteria-induced pH fall at the material surface was significantly inhibited. We conclude that S-PRG filler-containing coating resin may be an effective material for protecting exposed root from both chemical and biological challenges.