DIVERGENCE OF MEIOTIC DRIVE-SUPPRESSION SYSTEMS AS AN EXPLANATION FOR SEX-BIASED HYBRID STERILITY AND INVIABILITY
DIVERGENCE OF MEIOTIC DRIVE-SUPPRESSION SYSTEMS AS AN EXPLANATION FOR SEX-BIASED HYBRID STERILITY AND INVIABILITY
复制标题
DOI：
10.1111/j.1558-5646.1991.tb04401.x
复制
发表时间：
1991-03-01
期刊：
影响因子：
3.3
通讯作者：
FRANK, SA
中科院分区：
文献类型：
--
作者：
FRANK, SA
关于物种形成的两个经验概括仍然没有得到解释：在F1杂种中异配子性别的倾向是不育或不能存活的（Halfman规则），以及X染色体的倾向是隐藏导致这种杂种适应性性别偏见的遗传因素。我认为性染色体上减数分裂驱动系统的分歧可以解释这些观察结果。这个理论可以从两个简单的事实得出。首先，性染色体特别容易受到减数分裂驱动力的影响。其次，减数分裂驱动系统的分化可导致杂种不育和不活力。对这一理论的主要反对意见是，减数分裂驱动显然是罕见的，而观察到的杂交适合度模式是普遍存在的。我回答这个反对意见表明，分歧的减数分裂驱动系统可以解释这两个概括，即使大偏离孟德尔分离很少观察到。
Two empirical generalizations about speciation remain unexplained: the tendency of the heterogametic sex to be sterile or inviable in F1 hybrids (Haldane's rule), and the tendency of the X chromosome to harbor the genetic elements that cause this sex bias in hybrid fitness. I suggest that divergence of meiotic drive systems on the sex chromosomes can explain these observations. The theory follows from two simple facts. First, sex chromosomes are particularly susceptible to the forces of meiotic drive. Second, divergence of meiotic drive systems can cause hybrid sterility and inviability. The main objection to the theory is that meiotic drive is apparently rare, whereas the observed pattern of hybrid fitness is widespread. I answer this objection by showing that divergence of meiotic drive systems can explain the two generalizations even if large departures from Mendelian segregation are rarely observed.