STUDIES OF VENTROMEDIAL HYPOTHALAMIC AFFERENTS IN THE RAT USING 3 METHODS OF HRP APPLICATION
STUDIES OF VENTROMEDIAL HYPOTHALAMIC AFFERENTS IN THE RAT USING 3 METHODS OF HRP APPLICATION
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DOI：
10.1007/bf00274980
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发表时间：
1989-01-01
影响因子：
2
通讯作者：
PFAFF, DW
中科院分区：
文献类型：
--
作者：
FAHRBACH, SE;MORRELL, JI;PFAFF, DW
本文用辣根过氧化物酶（HRP）晶体植入法、HRP凝胶植入法和离子电渗沉积法研究了大鼠下丘脑腹内侧核（VMH）的传入神经联系。检查的情况下，逆行示踪剂最好局限于核的各个分区显示，隔区项目只到腹外侧VHM，和内侧视前区，吻侧外侧下丘脑，腹侧下托项目主要到腹外侧VMH。因此，含有最高密度的雌二醇集中神经元的VMH的细分部分（Morrell et al. 1986）比核的喙部和中央部分接收更大的输入集合。中央分区接收比内侧或外侧区域更受限的投影集合。这些研究表明，可能有部分解剖隔离的神经输入到VMH的各个细分。
The afferent neural connections of the ventromedial nucleus of the rat hypothalamus (VMH) have been studied in detail using three horseradish peroxidase (HRP) application methods: HRP crystal implants, HRP-gel implants, and iontophoretic deposition of the enzyme. Examination of the cases in which the retrograde tracer was best confined to various subdivisions of the nucleus revealed that the septal area projects only to the ventrolateral VHM, and that the medial preoptic area, rostral lateral hypothalamus, and the ventral subiculum project mainly to the ventrolateral VMH. Thus, the subdivision of the VMH that contains the highest density of estradiol-concentrating neurons (Morrell et al. 1986) receives a larger set of inputs than the rostal and central parts of the nucleus. The central subdivision receives a more restricted set of projections than either the medial or the lateral regions. These studies suggest that there may be partial anatomical segregation of neural inputs to the various subdivisions of the VMH.